# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA649929 | Binding | Antagonistic activity against labelled Bombesin receptor bb1 binding sites in rat olfactory bulb by using [125I]- [Tyr] bombesin in presence of [D-Phe-6] bombesin(6-13)ethyl ester; 0.31-1.3 | 1 | ALA1131372 | tissue-based format | Scientific Literature | ||
2. | ALA649930 | Functional | Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cells | 24 | ALA1131372 | cell-based format | Scientific Literature | ||
3. | ALA649931 | Binding | In vitro inhibition of acidification responses to NMB at the human Bombesin receptor bb1 expressed in CHO cells; 1-17 | 1 | ALA1131372 | cell-based format | Scientific Literature | ||
4. | ALA649932 | Functional | In vitro inhibition of bombesin-evoked increases in intracellular calcium level in CHO cells stably expressed human Bombesin receptor bb1; 1-6.6 | 1 | ALA1131372 | cell-based format | Scientific Literature | ||
5. | ALA700856 | Binding | Binding affinity for human neuromedin B(hNMB) receptor expressed in CHO cells | 61 | ALA1130494 | cell-based format | Scientific Literature | ||
6. | ALA1291102 | Binding | Displacement of [125I]-(Tyr4)-Bombesin from bombesin BB1 receptor at 1 to 3 uM | 1 | ALA1287688 | single protein format | Scientific Literature | ||
7. | ALA1057866 | Binding | Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells | Homo sapiens | 34 | ALA1152392 | cell-based format | Scientific Literature | |
8. | ALA1057868 | Binding | Ratio of benzodiazepine IC50 to compound IC50 for human neuromedin B receptor transfected in HEK293 cells | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature | |
9. | ALA1057872 | Functional | Antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 nM neuromedin B-induced myo-[3H]inositol phosphate accumulation after 60 mins by scintillation proximity assay | Homo sapiens | 2 | ALA1152392 | cell-based format | Scientific Literature | |
10. | ALA1057873 | Functional | Ratio of benzodiazepine IC50 to compound IC50 for antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 mM neuromedin B-induced myo-[3H]inositol phosphate accumulation | Homo sapiens | 1 | ALA1152392 | cell-based format | Scientific Literature | |
11. | ALA748694 | Functional | Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | 1 | ALA1145035 | cell-based format | Scientific Literature | ||
12. | ALA748695 | Functional | Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | 4 | ALA1145035 | cell-based format | Scientific Literature | ||
13. | ALA748696 | Functional | Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay. | 32 | ALA1145035 | cell-based format | Scientific Literature | ||
14. | ALA752220 | Functional | Agonistic activity was determined against human Neuromedin B receptor transfected in HEK293 cells as accumulation levels of inositol phosphate | 2 | ALA1146776 | cell-based format | Scientific Literature | ||
15. | ALA752221 | Binding | Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells | 28 | ALA1146776 | cell-based format | Scientific Literature | ||
16. | ALA872663 | Binding | Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cells | 20 | ALA1159192 | cell-based format | Scientific Literature | ||
17. | ALA752222 | Binding | Binding affinity against human NMB receptor was determined | 1 | ALA1159192 | single protein format | Scientific Literature | ||
18. | ALA752223 | Functional | Inhibition of the NMB evoked increases in chloride currents in xenopus oocytes expressing human NMB receptor | 1 | ALA1159192 | cell-based format | Scientific Literature | ||
19. | ALA752224 | Functional | Inhibition of the NMB induced acidification response at human NMB receptor expressed in CHO cell | 1 | ALA1159192 | cell-based format | Scientific Literature | ||
20. | ALA998540 | Binding | Binding affinity to neuromedin B receptor | 1 | ALA1152231 | single protein format | Scientific Literature |