# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3618962 | B | Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by fluorescent assay | Homo sapiens | 41 | assay format | Scientific Literature | ||
2. | ALA3618965 | B | Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysis | Homo sapiens | 38 | assay format | Scientific Literature | ||
3. | ALA3625417 | B | Inhibition of human BCATm after 10 mins by fluorescent assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
4. | ALA3795165 | B | Inhibition of human BCATm incubated for 10 mins by Amplex red- based fluorescence analysis | Homo sapiens | 42 | single protein format | Scientific Literature | ||
5. | ALA3812805 | B | Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins by Amplex red dye based L-GOx and HRP enzyme coupled assay | Homo sapiens | 24 | single protein format | Scientific Literature | ||
6. | ALA3812806 | B | Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase HPLC method | Homo sapiens | 8 | assay format | Scientific Literature | ||
7. | ALA4885535 | B | Biochemical assay (BCAT2) | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
8. | ALA4885539 | B | Cellular mechanistic assay – BCAA measurement (MDA-MB-231 cells) | Homo sapiens | 1 | cell-based format | Donated Chemical Probes - SGC Frankfurt | ||
9. | ALA5217582 | B | Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assay | Homo sapiens | 27 | single protein format | Scientific Literature |