# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3619311 | B | Activation of Egr1 in human AGS cells assessed as increase in cleaved caspase-3 level at 100 uM by Western blot analysis in presence of caspase-3 inhibitor Ac-DEVD-CHO | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
2. | ALA3619312 | B | Activation of Egr1 in human AGS cells assessed as increase in cleaved caspase-3 level at 100 uM by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
3. | ALA3619315 | B | Activation of Egr1 in human AGS cells assessed as increase in cleaved PARP level at 100 uM by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
4. | ALA3619316 | B | Activation of Egr1 in human AGS cells assessed as increase in cleaved caspase-9 level at 100 uM by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
5. | ALA3619317 | B | Activation of Egr1 in human AGS cells assessed as increase in cleaved caspase-7 level at 100 uM by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
6. | ALA3619322 | B | Activation of Egr1 in human AGS cells assessed as increase in intracellular accumulation of reactive oxygen species at 100 uM by H2DCFDA probe-based flow cytometric analysis relative to control | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
7. | ALA3619323 | B | Activation of Egr1 in human AGS cells assessed as increase in loss of mitochondrial membrane potential after 6 hrs by Rh-123 staining-based flow cytometric analysis relative to control | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
8. | ALA3619895 | B | Activation of Egr1 in human AGS cells assessed as downregulation of cyclin A expression at 12.5 to 100 uM by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
9. | ALA3619896 | B | Activation of Egr1 in human AGS cells assessed as downregulation of cyclin E expression at 12.5 to 100 uM by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
10. | ALA3619897 | B | Activation of Egr1 in human AGS cells assessed as upregulation of protein expression by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
11. | ALA3619898 | B | Activation of Egr1 in human AGS cells assessed as upregulation of p21 expression by Western blot analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
12. | ALA3619900 | B | Activation of Egr1 in human AGS cells assessed as upregulation of p21 mRNA expression by RT-qPCR analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
13. | ALA3619901 | B | Activation of Egr1 in human AGS cells assessed as upregulation of protein expression after 6 hrs by DAPI staining-based fluorescence microscopic analysis | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
14. | ALA3619902 | B | Activation of Egr1 in human AGS cells assessed as induction of p21 promoter activity by dual luciferase reporter gene assay | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
15. | ALA3619903 | B | Activation of Egr1 in human AGS cells assessed as induction of p21 promoter activity by ChIP assay | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
16. | ALA3619904 | B | Activation of Egr1 in human AGS cells assessed as increase in interaction with p21 promoter by dual luciferase reporter gene assay | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
17. | ALA3619905 | B | Activation of Egr1 in human AGS cells assessed as increase in interaction with p21 promoter by ChIP assay | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
18. | ALA3619907 | B | Activation of Egr1 in human AGS cells assessed as upregulation of p21 mRNA expression at 50 to 100 uM by RT-qPCR analysis in presence of si-Egr1 relative to control | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
19. | ALA3619908 | B | Activation of Egr1 in human AGS cells assessed as upregulation of protein expression at 50 to 100 uM by Western blot analysis in presence of si-Egr1 | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature | |
20. | ALA3619909 | B | Activation of Egr1 in human AGS cells assessed as upregulation of p21 expression at 50 to 100 uM by Western blot analysis in presence of si-Egr1 | Homo sapiens | 1 | ALA3616368 | cell-based format | Scientific Literature |