# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3626191 | B | Binding affinity to CRYAB (unknown origin) assessed as reduction in CRYAB-VEGFA protein interaction | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA4201164 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 0.4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
3. | ALA4201165 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
4. | ALA4201170 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
5. | ALA4201172 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
6. | ALA4201173 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells at 0.4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA4201174 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA4201175 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HLE-B3 cells at 0.4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
9. | ALA4201194 | B | Induction of redissolving of aggregated alpha-crystallin B R120G mutant (unknown origin) at 200 uM incubated for 24 hrs by ThT-fluorescence based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA4201199 | B | Induction of redissolving of aggregated alpha-crystallin B R120G mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA4201203 | B | Induction of redissolving of aggregated alpha-crystallin B R120G mutant (unknown origin) at 200 uM incubated for 24 hrs by transmission-electron-microscopy | Homo sapiens | 2 | single protein format | Scientific Literature | ||
12. | ALA4201213 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced cytotoxicity in human HeLa cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
13. | ALA4201214 | B | Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced cytotoxicity in human HLE-B3 cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay | Homo sapiens | 6 | cell-based format | Scientific Literature |