| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA927497 | B | Effect on LXR-mediated intracellular triglyceride level in human HepG2 cells after 4 to 5 days | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA927498 | B | Effect on LXR-mediated intracellular triglyceride level in human HepG2 cells after 4 to 5 days | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA894876 | B | Effect on LXR | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 4. | ALA2016083 | B | Induction of LXR-mediated ABCA1 expression in human Caco2 cells by quantigene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1047700 | F | Agonist activity at human recombinant LXR-LBD by Gal4beta transactivation assay | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 6. | ALA1047701 | F | Agonist activity at human recombinant LXR-LBD by Gal4beta transactivation assay relative to T0901317 | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 7. | ALA1111748 | F | Agonist activity at human LXR by transactivation assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA1111763 | F | Agonist activity at human LXR by transactivation assay relative to fenofibric acid | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA2175826 | B | Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA relative to 2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-5-methyl-11-methylene-5H-dibenzo[b,e]azepin-6(11H)-one | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA2175939 | B | Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA2176517 | B | Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production at 10 uM incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 12. | ALA2176518 | B | Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production at 30 uM incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 13. | ALA2210318 | F | Agonist activity at LXR in human THP1 cells assessed as increase in ApoE mRNA level at 1 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2210323 | F | Agonist activity at LXR in human THP1 cells assessed as induction of ABCG1 gene expression at 100 uM after 48 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2210749 | F | Agonist activity at LXR in human Caco2 cells assessed as decrease in NPC1L1 mRNA level at 100 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2210750 | F | Agonist activity at LXR in human Caco2 cells assessed as increase in ABCG8 mRNA level at 100 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA2210751 | F | Agonist activity at LXR in human Caco2 cells assessed as increase in ABCG5 mRNA level at 100 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA2210752 | F | Agonist activity at LXR in human Caco2 cells assessed as increase in ABCA1 mRNA level at 100 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA2210753 | F | Agonist activity at LXR in human THP1 cells assessed as increase in ApoE mRNA level at 100 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2210755 | F | Agonist activity at LXR in human THP1 monocytes assessed as increase in ABCG1 mRNA level at 100 uM after 48 hrs by qPCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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