| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2066307 | F | Antiproliferative activity against human MOLM13 cells expressing FLT3-ITD mutant | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 2. | ALA2064917 | F | Antitumor activity against human MOLM13 cells expressing FLT3-ITD mutant xenografted in athymic nude NU-Fox1 mouse assessed as tumor regression at 25 mg/kg, iv administered as single dose | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2064918 | F | Antitumor activity against human MOLM13 cells expressing FLT3-ITD mutant xenografted in athymic nude NU-Fox1 mouse assessed as tumor regression at 25 mg/kg, iv administered QD on days 1 to 5 and 8 to 12 measured up to 30 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA1810163 | F | Antiproliferation activity against human MOLM13 cells expressing FLT3 mutation assessed as cell viability after 72 hrs by MTS method | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 5. | ALA1810353 | F | Antitumor activity against human MOLM13 cells xenografted in iv dosed athymic nu/nu nude mouse assessed as inhibition of tumor growth administered qd for two weeks | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA1810354 | F | Antitumor activity against human MOLM13 cells xenografted in athymic nu/nu nude mouse assessed as inhibition of tumor growth at 10 mg/kg, iv qd administered for 1 to 5 and 8 to 12 days measured during first 5 days of treatment | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA1810362 | F | Antitumor activity against human MOLM13 cells xenografted in athymic nu/nu nude mouse assessed as inhibition of tumor growth at 10 mg/kg, iv qd administered for 1 to 5 and 8 to 12 days measured after 5 days of treatment | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA1810571 | F | Antitumor activity against human MOLM13 cells xenografted in athymic nu/nu nude mouse assessed as tumor growth regression at 50 mg/kg, iv qd administered for 1 to 5 and 8 to 12 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA1913948 | A | Drug uptake in human MOLM13 cells assessed as CD45 staining of cells at 1 uM after 1 hr using 7-AAD staining by flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1936734 | F | Antiproliferative activity against human MOLM13 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA1948115 | F | Growth inhibition of human MOLM13 cells after 48 hrs by WST-1 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA939219 | F | Induction of apoptosis in human MOLM13 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA939484 | F | Antiproliferative activity against human MOLM13 cells after 72 hrs by WST-1 assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 14. | ALA939489 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as minimal tumor volume ratio at 50 mg/kg, po bid treated for 5 days measured after 7 days relative to control | Homo sapiens | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA939490 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as minimal tumor volume ratio at 100 mg/kg, po bid treated for 5 days measured after 7 days relative to control | Homo sapiens | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA939491 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as tumor volume ratio at 200 mg/kg, po bid treated for 5 days measured after 10 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA939492 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as minimal tumor volume ratio at 100 mg/kg, po bid treated for 5 days measured after 10 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA939493 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as minimal regressive tumor volume ratio at 100 mg/kg, po bid treated for 5 days measured after 4 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA939494 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as minimal regressive tumor volume ratio at 200 mg/kg, po bid treated for 5 days measured after 10 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA939495 | F | Antitumor activity against human MOLM13 cells xenografted in SCID mouse assessed as minimal regressive tumor volume ratio at 50 mg/kg, po bid treated for 5 days measured after 7 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature |
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