# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3428313 | Binding | Inhibition of human GSK3alpha using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE peptide substrate at 1 uM by 33P Hotspot assay | Homo sapiens | 1 | ALA3425491 | single protein format | Scientific Literature | |
2. | ALA3533962 | Binding | Inhibition of GSK3alpha (unknown origin) | Homo sapiens | 1 | ALA3526091 | single protein format | Scientific Literature | |
3. | ALA3584794 | Binding | Inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as 33P incorporation into substrate peptide after 30 mins by beta scintillation counting analysis in presence of [33P]gamma-ATP | Homo sapiens | 1 | ALA3580650 | cell-based format | Scientific Literature | |
4. | ALA3584795 | Binding | Competitive inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as 33P incorporation into substrate peptide after 30 mins by beta scintillation counting analysis in presence of [33P]gamma-ATP | Homo sapiens | 1 | ALA3580650 | cell-based format | Scientific Literature | |
5. | ALA3595490 | Binding | Inhibition of human GSK3A at 0.1 uM relative to control | Homo sapiens | 1 | ALA3593229 | single protein format | Scientific Literature | |
6. | ALA3595347 | Binding | Inhibition of GSK-3alpha (unknown origin) at 1 uM relative to control | Homo sapiens | 1 | ALA3593241 | single protein format | Scientific Literature | |
7. | ALA3626288 | Binding | Inhibition of GSK3A (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3621137 | single protein format | Scientific Literature | |
8. | ALA3630516 | Binding | Inhibition of GSK3alpha (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
9. | ALA3635553 | Binding | Inhibition of human recombinant GSK-3 alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate incubated for 60 mins by LANCE method relative to control | Homo sapiens | 2 | ALA3632523 | single protein format | Scientific Literature | |
10. | ALA3635561 | Binding | Inhibition of GSK-3 alpha in human HL-60 cells assessed as decreased nuclear to cytoplasmic ratio at 5 to 10 uM after 6 days by May-Grunwald Giemsa staining based light microscopy | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
11. | ALA3635562 | Binding | Inhibition of GSK-3 alpha in human HL-60 cells assessed as reduction in GSK-3 alpha Tyr 279 phosphorylation up to 20 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
12. | ALA3635563 | Binding | Inhibition of GSK-3 alpha in human NB4 cells assessed as reduction in GSK-3 alpha Tyr 279 phosphorylation up to 20 uM after 24 hrs by immunoblotting | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
13. | ALA3635566 | Binding | Inhibition of GSK-3 alpha in human NB4 cells assessed as decreased nuclear to cytoplasmic ratio at 5 to 10 uM after 6 days by May-Grunwald Giemsa staining based light microscopy | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
14. | ALA3635567 | Binding | Inhibition of GSK-3 alpha in human HL-60 cells assessed as increased vacuolization at 5 to 10 uM after 6 days by May-Grunwald Giemsa staining based light microscopy | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
15. | ALA3635568 | Binding | Inhibition of GSK-3 alpha in human NB4 cells assessed as increased vacuolization at 5 to 10 uM after 6 days by May-Grunwald Giemsa staining based light microscopy | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
16. | ALA3635569 | Binding | Inhibition of GSK-3 alpha in human HL-60 cells assessed as CD11b expression at 5 to 10 uM after 6 days by flow cytometry | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
17. | ALA3635570 | Binding | Inhibition of GSK-3 alpha in human HL-60 cells assessed as CD11c expression at 5 to 10 uM after 6 days by flow cytometry | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
18. | ALA3635571 | Binding | Inhibition of GSK-3 alpha in human HL-60 cells assessed as CD14 expression at 5 to 10 uM after 6 days by flow cytometry | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
19. | ALA3635572 | Binding | Inhibition of GSK-3 alpha in human NB4 cells assessed as CD11b expression at 5 to 10 uM after 6 days by flow cytometry | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature | |
20. | ALA3635573 | Binding | Inhibition of GSK-3 alpha in human NB4 cells assessed as CD11c expression at 5 to 10 uM after 6 days by flow cytometry | Homo sapiens | 1 | ALA3632523 | cell-based format | Scientific Literature |