# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3562081 | Functional | PubChem BioAssay. Selectivity Studies of mglur8 probe at mglur6. (Class of assay: confirmatory) | 1 | ALA1201862 | assay format | PubChem BioAssays | ||
2. | ALA3607021 | Binding | Negative allosteric modulation at mGlu6 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3603801 | single protein format | Scientific Literature | |
3. | ALA3607072 | Binding | Positive allosteric modulation of mGlu6 receptor (unknown origin) | Homo sapiens | 1 | ALA3603827 | single protein format | Scientific Literature | |
4. | ALA3610758 | Functional | Activity at mGlu6 receptor (unknown origin) expressed in HEK293 cells pre-treated for 15 mins before addition of EC80 concentration of reference agonist for another 15 mins by cAMP accumulation assay | Homo sapiens | 1 | ALA3608268 | cell-based format | Scientific Literature | |
5. | ALA3619424 | Functional | Agonist activity at human recombinant mGlu6 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by fluorescence assay | Homo sapiens | 1 | ALA3616378 | cell-based format | Scientific Literature | |
6. | ALA3619425 | Functional | Agonist activity at human recombinant mGlu6 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by fluorescence assay relative to glutamate | Homo sapiens | 1 | ALA3616378 | cell-based format | Scientific Literature | |
7. | ALA3631337 | Binding | Positive allosteric modulation of mGlu6 receptor (unknown origin) assessed as potentiation of glutamate-induced response by cell-based assay | Homo sapiens | 3 | ALA3627606 | cell-based format | Scientific Literature | |
8. | ALA3637025 | Binding | Positive allosteric modulation of mGlu6 receptor (unknown origin) relative to control | Homo sapiens | 1 | ALA3632544 | single protein format | Scientific Literature | |
9. | ALA3769215 | Binding | Positive allosteric modulation of mGluR6 (unknown origin) | Homo sapiens | 1 | ALA3763140 | single protein format | Scientific Literature | |
10. | ALA3807556 | Binding | Positive allosteric modulation of mGlu6 receptor (unknown origin) | Homo sapiens | 9 | ALA3804754 | single protein format | Scientific Literature | |
11. | ALA3808090 | Binding | Positive allosteric modulation of mGlu6 receptor (unknown origin) | Homo sapiens | 1 | ALA3804767 | single protein format | Scientific Literature | |
12. | ALA3808091 | Binding | Negative allosteric modulation of mGlu6 receptor (unknown origin) | Homo sapiens | 1 | ALA3804767 | single protein format | Scientific Literature | |
13. | ALA3808092 | Binding | Agonist activity at mGlu6 receptor (unknown origin) | Homo sapiens | 1 | ALA3804767 | single protein format | Scientific Literature | |
14. | ALA718127 | Binding | Activity against Metabotropic glutamate receptor 6; Not active | 1 | ALA1133058 | single protein format | Scientific Literature | ||
15. | ALA718128 | Binding | Inhibition of c-AMP by human Metabotropic glutamate receptor 6 (mGluR6) expressed in non-neuronal cells | Homo sapiens | 9 | ALA1135971 | cell-based format | Scientific Literature | |
16. | ALA718129 | Binding | Inhibition of c-AMP by human Metabotropic glutamate receptor 6 (mGluR6) expressed in non-neuronal cells | Homo sapiens | 2 | ALA1135971 | cell-based format | Scientific Literature | |
17. | ALA718130 | Functional | Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6). | 22 | ALA1133464 | assay format | Scientific Literature | ||
18. | ALA712799 | Binding | Inhibition of c-AMP by human Metabotropic glutamate receptor 6 (mGluR6) expressed in non-neuronal cells | Homo sapiens | 3 | ALA1135971 | cell-based format | Scientific Literature | |
19. | ALA712215 | Functional | Agonistic activity at mGlu6 receptor expressed in CHO cells | 10 | ALA1129268 | cell-based format | Scientific Literature | ||
20. | ALA712387 | Functional | Agonistic activity at mGlu6 receptor expressed in CHO cells | 1 | ALA1129268 | cell-based format | Scientific Literature |