# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA713110 | B | Binding affinity is evaluated for human Melatonin receptor type 1A expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand); NT is not tested | 3 | ALA1133479 | cell-based format | Scientific Literature | ||
2. | ALA713111 | B | Binding affinity for human melatonin receptor type 1A, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand) | 38 | ALA1133479 | cell-based format | Scientific Literature | ||
3. | ALA713112 | B | Binding affinity is evaluated for human mt1 receptor, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand); NT is not tested | 1 | ALA1133479 | cell-based format | Scientific Literature | ||
4. | ALA713115 | B | Binding affinity against human Melatonin receptor type 1A by using 2-[125I]iodomelatonin as radioligand | 39 | ALA1146812 | single protein format | Scientific Literature | ||
5. | ALA713258 | B | Binding affinity towards human melatonin receptor type 1A | 38 | ALA1146665 | single protein format | Scientific Literature | ||
6. | ALA713259 | B | Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1A expressed in HEK293 cells | Homo sapiens | 12 | ALA1135933 | cell-based format | Scientific Literature | |
7. | ALA713260 | B | Binding affinity against Melatonin receptor type 1A | 33 | ALA1147462 | single protein format | Scientific Literature | ||
8. | ALA713261 | F | Inhibitory activity against human Melatonin receptor type 1A; agonist | 1 | ALA1131096 | assay format | Scientific Literature | ||
9. | ALA713262 | F | Inhibitory activity against human Melatonin receptor type 1A; antagonist | 7 | ALA1131096 | assay format | Scientific Literature | ||
10. | ALA715636 | B | Inhibitory activity against human Melatonin receptor type 1A; inactive | 3 | ALA1131096 | single protein format | Scientific Literature | ||
11. | ALA715637 | F | Inhibitory activity against human Melatonin receptor type 1A; partial agonist | 5 | ALA1131096 | assay format | Scientific Literature | ||
12. | ALA711324 | F | Inhibitory activity against human Melatonin receptor type 1A; partial agonist | 3 | ALA1131096 | assay format | Scientific Literature | ||
13. | ALA711325 | F | Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1A | Homo sapiens | 2 | ALA1136735 | cell-based format | Scientific Literature | |
14. | ALA711326 | F | Intrinsic activity evaluated on [35S]GTP -gamma-S binding in Chinese hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1A | Homo sapiens | 10 | ALA1135482 | cell-based format | Scientific Literature | |
15. | ALA710853 | F | Intrinsic activity evaluated on [35S]GTP -gamma-S binding in hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1A | Homo sapiens | 1 | ALA1135482 | cell-based format | Scientific Literature | |
16. | ALA710854 | F | Intrinsic activity of Melatonin receptor type 1A evaluated on [35S]GTP-gamma-S, binding in Chinese hamster ovarian (CHO) cells | Homo sapiens | 1 | ALA1135482 | cell-based format | Scientific Literature | |
17. | ALA710855 | F | Efficacy of [35S]GTP-gamma-S, binding to Melatonin receptor type 1A expressed in Chinese hamster ovarian (CHO) cells | Homo sapiens | 12 | ALA1135482 | cell-based format | Scientific Literature | |
18. | ALA710856 | B | Maximal efficacy expressed as percentage of that observed with 1 uM melatonin for Melatonin receptor type 1A | Homo sapiens | 3 | ALA1136735 | single protein format | Scientific Literature | |
19. | ALA714094 | F | Specific binding of [35S]GTP-gamma-S, to the alpha subunit of the G-protein-coupled Melatonin receptor type 1A was measured; expressed as % G-protein activation. | 17 | ALA1131096 | assay format | Scientific Literature | ||
20. | ALA714095 | F | Basal binding activity towards Melatonin receptor type 1A was measured by incubating with [35S]GTP-gamma-S (100 uM) and NaCl (700 mM). | 19 | ALA1131096 | assay format | Scientific Literature |