| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA713110 | B | Binding affinity is evaluated for human Melatonin receptor type 1A expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand); NT is not tested | 3 | cell-based format | Scientific Literature | |||
| 2. | ALA713111 | B | Binding affinity for human melatonin receptor type 1A, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand) | 38 | cell-based format | Scientific Literature | |||
| 3. | ALA713112 | B | Binding affinity is evaluated for human mt1 receptor, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand); NT is not tested | 1 | cell-based format | Scientific Literature | |||
| 4. | ALA713115 | B | Binding affinity against human Melatonin receptor type 1A by using 2-[125I]iodomelatonin as radioligand | 39 | single protein format | Scientific Literature | |||
| 5. | ALA713258 | B | Binding affinity towards human melatonin receptor type 1A | 38 | single protein format | Scientific Literature | |||
| 6. | ALA713259 | B | Inhibition of 2-[125I]iodomelatonin binding to human Melatonin receptor type 1A expressed in HEK293 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 7. | ALA713260 | B | Binding affinity against Melatonin receptor type 1A | 33 | single protein format | Scientific Literature | |||
| 8. | ALA713261 | F | Inhibitory activity against human Melatonin receptor type 1A; agonist | 1 | assay format | Scientific Literature | |||
| 9. | ALA713262 | F | Inhibitory activity against human Melatonin receptor type 1A; antagonist | 7 | assay format | Scientific Literature | |||
| 10. | ALA715636 | B | Inhibitory activity against human Melatonin receptor type 1A; inactive | 3 | single protein format | Scientific Literature | |||
| 11. | ALA715637 | F | Inhibitory activity against human Melatonin receptor type 1A; partial agonist | 5 | assay format | Scientific Literature | |||
| 12. | ALA711324 | F | Inhibitory activity against human Melatonin receptor type 1A; partial agonist | 3 | assay format | Scientific Literature | |||
| 13. | ALA711325 | F | Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1A | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA711326 | F | Intrinsic activity evaluated on [35S]GTP -gamma-S binding in Chinese hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1A | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 15. | ALA710853 | F | Intrinsic activity evaluated on [35S]GTP -gamma-S binding in hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1A | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA710854 | F | Intrinsic activity of Melatonin receptor type 1A evaluated on [35S]GTP-gamma-S, binding in Chinese hamster ovarian (CHO) cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA710855 | F | Efficacy of [35S]GTP-gamma-S, binding to Melatonin receptor type 1A expressed in Chinese hamster ovarian (CHO) cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA710856 | B | Maximal efficacy expressed as percentage of that observed with 1 uM melatonin for Melatonin receptor type 1A | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA714094 | F | Specific binding of [35S]GTP-gamma-S, to the alpha subunit of the G-protein-coupled Melatonin receptor type 1A was measured; expressed as % G-protein activation. | 17 | assay format | Scientific Literature | |||
| 20. | ALA714095 | F | Basal binding activity towards Melatonin receptor type 1A was measured by incubating with [35S]GTP-gamma-S (100 uM) and NaCl (700 mM). | 19 | assay format | Scientific Literature |
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