| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA712996 | F | Effective concentration against human MT2 (Melatonin) receptor stably expressed in NIH3T3 cells in adenylyl cyclase assay | 1 | ALA1136666 | cell-based format | Scientific Literature | ||
| 2. | ALA713589 | F | Intrinsic activity was determined against human MT2 (Melatonin) receptor stably expressed in NIH3T3 cells in adenylyl cyclase assay | 1 | ALA1136666 | cell-based format | Scientific Literature | ||
| 3. | ALA712574 | B | Binding affinity for melatonin receptor type 1B, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand) | 38 | ALA1133479 | cell-based format | Scientific Literature | ||
| 4. | ALA712575 | B | Binding affinity is evaluated for Melatonin receptor type 1B, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand); NT is not tested | 2 | ALA1133479 | cell-based format | Scientific Literature | ||
| 5. | ALA709921 | B | Binding affinity is evaluated for human MT2 receptor, expressed in HEK293 cells (2-[125I]iodomelatonin is used as radioligand); NT is not tested | 1 | ALA1133479 | cell-based format | Scientific Literature | ||
| 6. | ALA709922 | B | Binding affinity against melatonin receptor type 1B | 34 | ALA1147462 | single protein format | Scientific Literature | ||
| 7. | ALA709923 | F | Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1B | Homo sapiens | 2 | ALA1136735 | cell-based format | Scientific Literature | |
| 8. | ALA709924 | F | Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]GTP-gamma-S, binding in Chinese hamster ovarian (CHO) cells | Homo sapiens | 1 | ALA1135482 | cell-based format | Scientific Literature | |
| 9. | ALA710586 | F | Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]GTP-gamma-S, binding in Chinese hamster ovarian (CHO) cells | Homo sapiens | 11 | ALA1135482 | cell-based format | Scientific Literature | |
| 10. | ALA710587 | F | Efficacy of [35S]GTP-gamma-S, binding to Melatonin receptor type 1B expressed in Chinese hamster ovarian (CHO) cells | Homo sapiens | 12 | ALA1135482 | cell-based format | Scientific Literature | |
| 11. | ALA710588 | B | Maximal efficacy expressed as percentage of that observed with 1 uM melatonin for Melatonin receptor type 1B | Homo sapiens | 3 | ALA1136735 | single protein format | Scientific Literature | |
| 12. | ALA710589 | F | Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1B | Homo sapiens | 1 | ALA1136735 | cell-based format | Scientific Literature | |
| 13. | ALA710590 | B | The relative intrinsic values (IAr) of melatonin receptor type 1B obtained by dividing the maximal analogue-induced G-protein activation by that MLT. | 27 | ALA1134444 | single protein format | Scientific Literature | ||
| 14. | ALA710591 | B | In vitro receptor binding at MT2 (Melatonin) receptor. | 21 | ALA1136666 | single protein format | Scientific Literature | ||
| 15. | ALA710592 | B | Intrinsic activity (IAr) towards human Melatonin receptor type 1B | 1 | ALA1136758 | single protein format | Scientific Literature | ||
| 16. | ALA710593 | F | Intrinsic activity evaluated on [35S]GTP-gamma-S, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1B | 3 | ALA1136758 | cell-based format | Scientific Literature | ||
| 17. | ALA710749 | F | Relative Intrinsic activity evaluated on [35S]GTP-gamma-S, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1B | 36 | ALA1136758 | cell-based format | Scientific Literature | ||
| 18. | ALA880756 | F | Antagonist potency against effect of melatonin (3 nM) determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1B | Homo sapiens | 3 | ALA1136735 | cell-based format | Scientific Literature | |
| 19. | ALA710750 | F | Antagonist potency determined against 3 nM melatonin for Melatonin receptor type 1B | Homo sapiens | 10 | ALA1135482 | assay format | Scientific Literature | |
| 20. | ALA710751 | B | Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as radioligand | Homo sapiens | 9 | ALA1136735 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!