#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA658645	B	Inhibitory activity against Caspase-5		9		single protein format	Scientific Literature
2.	ALA832837	B	Inhibitory concentration against human caspase-5 in neuronal precursor (NT2) cells	Homo sapiens	1		assay format	Scientific Literature
3.	ALA832948	B	Inhibitory concentration against casp-5 in neuronal precursor (NT2) cells	Homo sapiens	1		assay format	Scientific Literature
4.	ALA867550	B	Inhibition of human recombinant caspase5 upto 50 uM	Homo sapiens	11		single protein format	Scientific Literature
5.	ALA913575	B	Inhibition of human caspase 5	Homo sapiens	1		single protein format	Scientific Literature
6.	ALA1040857	B	Inhibition of human Caspase 5	Homo sapiens	1		single protein format	Scientific Literature
7.	ALA1045480	B	Inhibition of caspase 5 assessed as residual activity at 10 uM after 10 to 15 mins by fluorescence assay relative to control		1		single protein format	Scientific Literature
8.	ALA1039234	B	Inhibition of caspase 5 after 10 to 15 mins by fluorescence assay		1		single protein format	Scientific Literature
9.	ALA1677855	B	Inhibition of human caspase-5 at 10 uM	Homo sapiens	1		single protein format	Scientific Literature
10.	ALA2327250	B	Inhibition of caspase-5 (unknown origin)	Homo sapiens	5		single protein format	Scientific Literature
11.	ALA2346359	B	Inhibition of Caspase 5 (unknown origin) using Ac-LEHD-AMC substrate assessed as residual activity at 10 uM incubated for 15 mins prior to substrate addition measured for 2 hrs	Homo sapiens	1		single protein format	Scientific Literature
12.	ALA3387100	B	Inhibition of recombinant human caspase 5 using LEHDGP substrate at up to 20 uM after 3 hrs	Homo sapiens	3		single protein format	Scientific Literature
13.	ALA3387748	B	Inhibition of recombinant human caspase 5 using LEHDGP substrate at up to 5 uM after 3 hrs	Homo sapiens	2		single protein format	Scientific Literature
14.	ALA3707901	B	Fluorometric Enzymatic Assay: The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)FMK (comparison control compound, SM Biochemicals LLC, Cat# SMFMK003)) and their respective IC50 values were determined using a fluorometric enzymatic assay (Active Recombinant Caspase Set IV (BioVision, Cat# K233-10-25) and Caspase Fluorometric Substrate Set II Plus (BioVision, Cat# K137-9-25)) on a Flexstation 3x (Molecular Devices). In brief, each compound was serially diluted for a final test concentration range of 0.1 nM to 3.3 uM (10-point titration). Each active recombinant Caspase (Active Recombinant Caspase Set IV (BioVision, Cat# K233-10-25)) was added to the respective wells of the 96-well High Efficiency plates (Molecular Devices, Cat#75-000-0005), followed by the addition of the diluted test compounds. DMSO (Final=1%) or Z-VAD-FMK (Caspase-Family Inhibitor, Z-VAD-FMK (BioVision, Cat#1010-100).	Homo sapiens	3		single protein format	BindingDB Database
15.	ALA3707828	B	Fluorometric Enzymatic Assay: Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspase-9 (group II) and caspase-3 and caspase-7 (group III) was evaluated by using fluorometric methods using the Caspase-1, -3, -5, -7, -9 Inhibitor Drug Screening Kit (Catalog #: K151-100, K153-100, K155-100/K157-100, K159-100 respectively, BioVision). Briefly, using instructions of the manufacturer, a wide range of different concentrations of the compound: 3333, 1000, 333, 100, 33, 10, 3, and 1 nM (final concentration) was added directly to the reaction mixtures containing the substrate and the enzyme in a final volume of 10 ul. After a 30-minute incubation at 37 C., the liberation of AFC was measured as an endpoint assay using the Flexstation3 (Molecular Devices) with an excitation wavelength of 400 nm and an emission wavelength of 505 nm. The level of inhibition of caspase-1, -3, -5, -7, -9 activity was determined by comparison.	Homo sapiens	26		single protein format	BindingDB Database
16.	ALA3864979	B	Inhibition of human recombinant DTT-activated caspase-5 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay	Homo sapiens	15		assay format	Scientific Literature
17.	ALA3864984	B	Inhibition of human recombinant DTT-activated caspase-5 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 15 mins followed by substrate addition by fluorescence assay	Homo sapiens	1		assay format	Scientific Literature
18.	ALA3864985	B	Inhibition of human recombinant DTT-activated caspase-5 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 45 mins followed by substrate addition by fluorescence assay	Homo sapiens	1		assay format	Scientific Literature
19.	ALA3864986	B	Ratio of IC50 for human recombinant DTT-activated caspase-5 expressed in Escherichia coli preincubated for 15 mins followed by Ac-WEHD-AMC substrate addition to IC50 for human recombinant DTT-activated caspase-5 expressed in Escherichia coli preincubated for 30 mins followed by Ac-WEHD-AMC substrate addition	Homo sapiens	1		assay format	Scientific Literature
20.	ALA3864987	B	Ratio of IC50 for human recombinant DTT-activated caspase-5 expressed in Escherichia coli preincubated for 15 mins followed by Ac-WEHD-AMC substrate addition to IC50 for human recombinant DTT-activated caspase-5 expressed in Escherichia coli preincubated for 45 mins followed by Ac-WEHD-AMC substrate addition	Homo sapiens	1		assay format	Scientific Literature