# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA746894 | F | Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activity | 24 | ALA1134619 | cell-based format | Scientific Literature | ||
2. | ALA746895 | F | In vitro concentration required to inhibit NHE-1 mediated intracellular maximal pH recovery by 50% | 7 | ALA1134237 | cell-based format | Scientific Literature | ||
3. | ALA873248 | F | Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | 21 | ALA1146688 | cell-based format | Scientific Literature | ||
4. | ALA832458 | B | Inhibitory activity against Na+/H+ exchanger 1 (NHE-1) expressed in PS120 cells | Homo sapiens | 52 | ALA1143601 | cell-based format | Scientific Literature | |
5. | ALA831381 | B | Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cells | Homo sapiens | 32 | ALA1139613 | cell-based format | Scientific Literature | |
6. | ALA856311 | B | Inhibition of human NHE1 expressed in Ap1 cell line | Homo sapiens | 24 | ALA1149356 | cell-based format | Scientific Literature | |
7. | ALA908033 | B | Inhibition of human NHE1 expressed in Ap1 cell line at 1 uM | Homo sapiens | 1 | ALA1149356 | cell-based format | Scientific Literature | |
8. | ALA895927 | B | Inhibition of human NHE1 expressed in PS120 cells | Homo sapiens | 40 | ALA1148836 | cell-based format | Scientific Literature | |
9. | ALA938727 | B | Inhibition of human wild type NHE1 expressed in chinese hamster AP1 cells assessed as intracellular pHi recovery by ammonium chloride prepulse protocol | Homo sapiens | 4 | ALA1156466 | cell-based format | Scientific Literature | |
10. | ALA963312 | B | Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosis | Homo sapiens | 38 | ALA1153272 | cell-based format | Scientific Literature | |
11. | ALA1912991 | B | Inhibition of NHE1 | 1 | ALA1909623 | single protein format | Scientific Literature | ||
12. | ALA1912993 | B | Ratio of compound K0.5 to amiloride K0.5 for NHE1 | 4 | ALA1909623 | single protein format | Scientific Literature | ||
13. | ALA2173433 | B | Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 mins in presence of plasma protein | Homo sapiens | 3 | ALA2169836 | cell-based format | Scientific Literature | |
14. | ALA2173434 | B | Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 mins | Homo sapiens | 51 | ALA2169836 | cell-free format | Scientific Literature | |
15. | ALA2173435 | B | Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 mins | Homo sapiens | 51 | ALA2169836 | cell-based format | Scientific Literature | |
16. | ALA3861047 | B | Inhibition of human NHE1 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Homo sapiens | 1 | ALA3860060 | cell-based format | Scientific Literature | |
17. | ALA3881452 | B | Inhibition of human NHE1 expressed in chinese hamster AP1 cells preincubated for 7.5 mins followed by addition of NaCl measured after 5 mins by BACEF-AM dye based fluorescence analysis | Homo sapiens | 3 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
18. | ALA3881456 | B | Inhibition of human NHE1 expressed in CHO-K1 cells assessed as inhibition of Na+/Ca+ exchange activity measured after 5 mins by BACEF-AM dye based fluorescence analysis | Homo sapiens | 1 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
19. | ALA3881459 | B | Inhibition of human NHE1 expressed in chinese hamster LAP1 cells assessed as reduction in pHi recovery measured for 400 secs by BACEF-AM dye based fluorescence analysis | Homo sapiens | 4 | ALA3880442 | cell-based format | Patent Bioactivity Data | |
20. | ALA3882215 | B | Inhibition of NHE-1 (unknown origin) | Homo sapiens | 8 | ALA3881530 | single protein format | Patent Bioactivity Data |