# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA653963 | B | Compound was evaluated for its effect on the activity of mammalian Carbamoyl-phosphate synthetase in the multienzyme polypeptide CAD at a concentration of 0.4mM | 3 | ALA1129083 | single protein format | Scientific Literature | ||
2. | ALA653964 | B | Compound was evaluated for its effect on the activity of mammalian Carbamoyl-phosphate synthetase in the multienzyme polypeptide CAD at a concentration of 1.2mM | 3 | ALA1129083 | single protein format | Scientific Literature | ||
3. | ALA653965 | B | Compound was evaluated for its effect on the activity of mammalian Carbamoyl-phosphate synthetase in the multienzyme polypeptide CAD at a concentration of 1.6mM | 2 | ALA1129083 | single protein format | Scientific Literature | ||
4. | ALA653966 | B | Compound was evaluated for its effect on the activity of mammalian Carbamoyl-phosphate synthetase in the multienzyme polypeptide CAD at a concentration of 4mM | 1 | ALA1129083 | single protein format | Scientific Literature | ||
5. | ALA653967 | B | Compound was evaluated for its effect on the activity of mammalian Carbamoyl-phosphate synthetase in the multienzyme polypeptide CAD at a concentration of 1.2 mM | 1 | ALA1129083 | single protein format | Scientific Literature | ||
6. | ALA666234 | B | Inhibitory activity against Dihydroorotase (DHO) using CAD protein at concentrations >=6 mM; no inhibition was observed | Cricetulus griseus | 1 | ALA1124703 | single protein format | Scientific Literature | |
7. | ALA663680 | B | Inhibitory activity against Dihydroorotase (DHO); no reproducible apparent Ki data | Cricetulus griseus | 1 | ALA1124703 | single protein format | Scientific Literature | |
8. | ALA876720 | B | Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in Escherichia coli. | Cricetulus griseus | 4 | ALA1131174 | assay format | Scientific Literature | |
9. | ALA663681 | B | Inhibitory activity against Dihydroorotase (DHO) at pH 6.0 | Cricetulus griseus | 1 | ALA1124703 | single protein format | Scientific Literature | |
10. | ALA663682 | B | Inhibitory activity against Dihydroorotase (DHO) at pH 7.4 and 8.5 | Cricetulus griseus | 1 | ALA1124703 | single protein format | Scientific Literature | |
11. | ALA858734 | B | Inhibitory activity against dihydroorotase isolated from 165-23 cells of Syrian hamster kidney cells at a concentration of 0.1-1000 uM; No effect | Cricetulus griseus | 4 | ALA1124150 | cell-based format | Scientific Literature | |
12. | ALA663683 | B | Kinetic constant for the inactivation against Dihydroorotase (DHO) at a concentration of 3 uM | Cricetulus griseus | 1 | ALA1124703 | single protein format | Scientific Literature | |
13. | ALA663684 | B | Kinetic constant for the inactivation of Dihydroorotase (DHO) at pH 6.0 | Cricetulus griseus | 1 | ALA1124703 | single protein format | Scientific Literature | |
14. | ALA4118734 | B | Binding affinity to CAD in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | ALA4118021 | cell-based format | Scientific Literature | |
15. | ALA4118890 | B | Binding affinity to CAD in human NCI-H358 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | ALA4118021 | cell-based format | Scientific Literature | |
16. | ALA4619225 | A | Inhibition of CAD (unknown origin) CSP2 activity expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins followed by ATP addition measured after 60 mins by ADP-Glo assay | Homo sapiens | 1 | ALA4616711 | assay format | Scientific Literature |