# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3825093 | Binding | Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-8 and human EAAT3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluo-4 AM dye based fluorescence imaging plate reader method | Homo sapiens | 16 | ALA3822422 | cell-based format | Scientific Literature | |
2. | ALA3825094 | Binding | Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-2 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluo-4 AM dye based fluorescence imaging plate reader method | Homo sapiens | 15 | ALA3822422 | cell-based format | Scientific Literature | |
3. | ALA3825095 | Binding | Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method | Homo sapiens | 2 | ALA3822422 | cell-based format | Scientific Literature | |
4. | ALA3825096 | Binding | Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-4 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluorescence imaging plate reader method | Homo sapiens | 2 | ALA3822422 | cell-based format | Scientific Literature | |
5. | ALA3825097 | Binding | Antagonist activity at human iGluA1 receptor flip isoform expressed in CHO-S cells assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluo-4 NW dye based fluorescence imaging plate reader method | Homo sapiens | 15 | ALA3822422 | cell-based format | Scientific Literature | |
6. | ALA680869 | Binding | Inhibition of the (-40 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA. | 20 | ALA1135693 | cell-based format | Scientific Literature | ||
7. | ALA680870 | Binding | Inhibition of the (-80 mV) current elicited by 100 uM glutamate by simultaneous co-application in xenopus oocytes injected with GluR1 flop RNA. | 20 | ALA1135693 | cell-based format | Scientific Literature | ||
8. | ALA884410 | Binding | Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 1 (GluR1o) | Xenopus laevis | 3 | ALA1144920 | cell-based format | Scientific Literature | |
9. | ALA701238 | Binding | In vitro inhibitory activity against Ionotropic glutamate receptor AMPA 1 of HEK293 cells in FLIPR assay | 2 | ALA1145950 | cell-based format | Scientific Literature | ||
10. | ALA701239 | Binding | Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1 | 3 | ALA1136004 | single protein format | Scientific Literature | ||
11. | ALA878883 | Binding | Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 1 expressed in HEK293 cells | Homo sapiens | 14 | ALA1130220 | cell-based format | Scientific Literature | |
12. | ALA701240 | Binding | Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 1 using cell membranes prepared from HEK293 cells | 7 | ALA1133269 | cell-based format | Scientific Literature | ||
13. | ALA701241 | Binding | Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 1 in HEK293 cells using [3H]-AMPA as radioligand | 4 | ALA1133179 | cell-based format | Scientific Literature | ||
14. | ALA701247 | Binding | Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 1 (GluR1) expressed in Sf 9 insect cells | 3 | ALA1144891 | cell-based format | Scientific Literature | ||
15. | ALA829619 | Binding | Binding affinity for ionotropic Glutamate receptor AMPA 1 expressed in Sf9 cells | 5 | ALA1144430 | cell-based format | Scientific Literature | ||
16. | ALA863279 | Functional | Inhibitory effect on glutamate-induced calcium influx at homomeric human GLUA1 receptor expressed in HEK293 cells up to 300 uM | Homo sapiens | 1 | ALA1141230 | cell-based format | Scientific Literature | |
17. | ALA865008 | Functional | Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA1 up to 100 uM | Homo sapiens | 1 | ALA1146072 | cell-based format | Scientific Literature | |
18. | ALA865014 | Functional | Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA1 | Homo sapiens | 1 | ALA1146072 | cell-based format | Scientific Literature | |
19. | ALA895662 | Functional | Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assay | 6 | ALA1148746 | cell-based format | Scientific Literature | ||
20. | ALA895663 | Functional | Agonist activity at GluR1 expressed in HEK293 cells relative to S-Glutamate by Fluo-4/Ca2+ assay | 4 | ALA1148746 | cell-based format | Scientific Literature |