| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA680371 | F | In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees for 30 min in presence of 50 nM [3H]glycine. | 26 | assay format | Scientific Literature | |||
| 2. | ALA909052 | B | Inhibition of rat GlyT1 | Rattus norvegicus | 20 | single protein format | Scientific Literature | ||
| 3. | ALA1657779 | B | Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cells | Rattus norvegicus | 30 | cell-based format | Scientific Literature | ||
| 4. | ALA1657782 | B | Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cells at 100 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1657784 | B | Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cells at 10 uM | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA1657806 | B | Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cells at 30 uM | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1932648 | B | Displacement of [3H]glycine from rat GlyT1 expressed in rat C6 cells after 30 mins by scintillation counting | Rattus norvegicus | 19 | cell-based format | Scientific Literature | ||
| 8. | ALA1932707 | B | Displacement of [3H]glycine from rat GlyT1 expressed in rat C6 cells at 10 uM after 30 mins by scintillation counting | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA1944187 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor ALX5407 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 10. | ALA1944188 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 1 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 11. | ALA1944189 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 10 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 12. | ALA1944190 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT2 inhibitor ORG25543 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 13. | ALA1944191 | B | Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM NMDA receptor glycine site antagonist L-701,324 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA1944192 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 15. | ALA1944193 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of GlyT1 inhibitor N-Me-SSR504734 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 16. | ALA1944194 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor HPCP relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 17. | ALA1944195 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT1 inhibitor ALX5407 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 18. | ALA1944196 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 1 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 19. | ALA1944197 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 10 mM GlyT1 substrate glycine relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 20. | ALA1944198 | B | Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM GlyT2 inhibitor ORG25543 relative to control | Rattus norvegicus | 1 | tissue-based format | Scientific Literature |
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