# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3705997 | Binding | Inhibition Assay: Thoroughly mixed test compounds, enzyme and reaction buffer, preincubated the mixture for 15 minutes at 37° C. and then primed reaction by adding substrate, successfully detecting fluorescence value at 460 nm for 5 minutes. At the same time, set the blank control group without substrate and solvent control group with DMSO replacing test compound, as well as positive control group of Vildagliptin (LAF-237) and Sitagliptin (MK-0431) [Bioorg. Med. Chem. Lett., 2005, 15, 4770-4773]. All final reaction volumes were 100 μL. Each concentration of each sample consisted of parallel wells in triplate. | Rattus norvegicus | 9 | ALA3638422 | single protein format | BindingDB Database | |
2. | ALA664523 | Binding | In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasma | 2 | ALA1135431 | cell-free format | Scientific Literature | ||
3. | ALA664524 | Binding | In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasma. | 1 | ALA1135431 | cell-free format | Scientific Literature | ||
4. | ALA664525 | Binding | Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from rat plasma | 2 | ALA1145816 | cell-free format | Scientific Literature | ||
5. | ALA664526 | Binding | Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from rat plasma | 2 | ALA1145816 | cell-free format | Scientific Literature | ||
6. | ALA664527 | Binding | Inhibitory activity against Dipeptidylpeptidase IV in rat | 26 | ALA1148254 | assay format | Scientific Literature | ||
7. | ALA832543 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 6 hr | Rattus norvegicus | 1 | ALA1140346 | assay format | Scientific Literature | |
8. | ALA832544 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 2 hr | Rattus norvegicus | 1 | ALA1140346 | assay format | Scientific Literature | |
9. | ALA832545 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 2 hr | Rattus norvegicus | 1 | ALA1140346 | assay format | Scientific Literature | |
10. | ALA832546 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 4 hr | Rattus norvegicus | 1 | ALA1140346 | assay format | Scientific Literature | |
11. | ALA832547 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 4 hr | Rattus norvegicus | 1 | ALA1140346 | assay format | Scientific Literature | |
12. | ALA832548 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 6 hr | Rattus norvegicus | 1 | ALA1140346 | assay format | Scientific Literature | |
13. | ALA832549 | Functional | Effective dose for inhibition of Dipeptidyl peptidase IV in prediabetic rat model after 0.5 hr | Rattus norvegicus | 2 | ALA1140346 | assay format | Scientific Literature | |
14. | ALA832699 | Binding | Inhibitory concentration against rat dipeptidylpeptidase IV | Rattus norvegicus | 18 | ALA1145239 | single protein format | Scientific Literature | |
15. | ALA877009 | Binding | Inhibitory activity against dipeptidyl peptidase IV (DP-IV) | Rattus norvegicus | 16 | ALA1141998 | single protein format | Scientific Literature | |
16. | ALA874548 | Binding | Inhibitory concentration against rat dipeptidyl peptidase IV | Rattus norvegicus | 20 | ALA1137181 | single protein format | Scientific Literature | |
17. | ALA830872 | Binding | Inhibitory activity against dipeptidyl peptidase IV (DP-IV); NA: Not available | Rattus norvegicus | 12 | ALA1141998 | single protein format | Scientific Literature | |
18. | ALA831628 | Functional | Ex vivo Dipeptidyl peptidase IV inhibition in rat plasma after 4 hr 4 umol/kg peroral dose | Rattus norvegicus | 4 | ALA1140346 | cell-free format | Scientific Literature | |
19. | ALA836269 | Functional | Ex vivo percent inhibition of Dipeptidyl peptidase IV in rat plasma after 30 min at 4 umol/kg peroral dose | Rattus norvegicus | 15 | ALA1140346 | cell-free format | Scientific Literature | |
20. | ALA835487 | Functional | Ex vivo percent inhibition of Dipeptidyl peptidase IV in rat plasma after 4 hr at 4 umol/kg peroral dose | Rattus norvegicus | 11 | ALA1140346 | cell-free format | Scientific Literature |