# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3562125 | Functional | PubChem BioAssay. Extended Characterization of HPGD Inhibitors: Counterscreen Against ALDH1A1. (Class of assay: confirmatory) | Homo sapiens | 218 | ALA1201862 | assay format | PubChem BioAssays | |
2. | ALA1110890 | Binding | Inhibition of ALDH1 in human K562 cells at 15 uM after 45 mins by flow cytometry based method relative to bodipy-aminoacetaldehyde | Homo sapiens | 6 | ALA1157084 | cell-based format | Scientific Literature | |
3. | ALA3421185 | Binding | Competitive inhibition of recombinant human ALDH1A1 using 800 uM NAD+ as cofactor by Lineweaver-Burk plot analysis in presence of 100 to 800 uM acetaldehyde | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
4. | ALA3421186 | Binding | Inhibition of recombinant human ALDH1A1 using propionaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis relative to control | Homo sapiens | 5 | ALA3414499 | single protein format | Scientific Literature | |
5. | ALA3421198 | Binding | Uncompetitive partial inhibition of recombinant human ALDH1A1 using 200 uM propionaldehyde as substrate by Lineweaver-Burk plot analysis in presence of 25 to 250 uM NAD+ | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
6. | ALA3418007 | Binding | Effect on recombinant human ALDH1A1 using propionaldehyde as substrate up to 250 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 2 | ALA3414499 | single protein format | Scientific Literature | |
7. | ALA3418008 | Binding | Non-competitive tight inhibition of recombinant human ALDH1A1 using 1000 uM NAD+ as cofactor by Lineweaver-Burk plot analysis in presence of 100 to 800 uM acetaldehyde | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
8. | ALA3418009 | Binding | Competitive tight inhibition of recombinant human ALDH1A1 using 1000 uM NAD+ as cofactor by Lineweaver-Burk plot analysis in presence of 100 to 800 uM acetaldehyde | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
9. | ALA3418010 | Binding | Inhibition of human ALDH1A1 G458N mutant using propionaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis relative to control | Homo sapiens | 17 | ALA3414499 | single protein format | Scientific Literature | |
10. | ALA3418011 | Binding | Inhibition of human ALDH1A1 G458N mutant using propionaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
11. | ALA3418216 | Binding | Inhibition of human ALDH1A1 G458N mutant using propionaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 2 | ALA3414499 | single protein format | Scientific Literature | |
12. | ALA3418217 | Binding | Inhibition of recombinant human ALDH1A1 using propionaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
13. | ALA3419576 | Binding | Inhibition of recombinant human ALDH1A1 using propionaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 20 | ALA3414499 | single protein format | Scientific Literature | |
14. | ALA3419577 | Binding | Non-competitive partial inhibition of recombinant human ALDH1A1 using 800 uM NAD+ as cofactor by Lineweaver-Burk plot analysis in presence of 100 to 800 uM acetaldehyde | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
15. | ALA1738585 | Functional | PUBCHEM_BIOASSAY: Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1): Follow up Confirmation and Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1030, AID2407] | Homo sapiens | 84 | ALA1201862 | assay format | PubChem BioAssays | |
16. | ALA997768 | Binding | Inhibition of ALDH1 in human DU145 cells at 2.5 uM after 3 days | Homo sapiens | 2 | ALA1156669 | cell-based format | Scientific Literature | |
17. | ALA997769 | Binding | Inhibition of ALDH1 in human DU145 cells at 5 uM after 3 days | Homo sapiens | 2 | ALA1156669 | cell-based format | Scientific Literature | |
18. | ALA997770 | Binding | Inhibition of ALDH1 in human DU145 cells at 7.5 uM after 3 days | Homo sapiens | 2 | ALA1156669 | cell-based format | Scientific Literature | |
19. | ALA997777 | Binding | Inhibition of ALDH1 | 1 | ALA1156669 | single protein format | Scientific Literature | ||
20. | ALA1019415 | Binding | Effect on human recombinant his-tagged cytosolic ALDH1A1 activity expressed in Escherichia coli BL21 cells at 100 uM | Homo sapiens | 1 | ALA1152868 | cell-based format | Scientific Literature |