# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA997771 | B | Inhibition of ALDH3 in human DU145 cells at 2.5 uM after 3 days | Homo sapiens | 2 | ALA1156669 | cell-based format | Scientific Literature | |
2. | ALA997772 | B | Inhibition of ALDH3 in human DU145 cells at 5 uM after 3 days | Homo sapiens | 2 | ALA1156669 | cell-based format | Scientific Literature | |
3. | ALA997773 | B | Inhibition of ALDH3 in human DU145 cells at 7.5 uM after 3 days | Homo sapiens | 2 | ALA1156669 | cell-based format | Scientific Literature | |
4. | ALA3118113 | B | Inhibition of ALDH3A1 in human SF-767 cells assessed as reduction of mafosfamide ED50 at 10 uM after 19 hrs by MTT assay relative to control | Homo sapiens | 3 | ALA3112389 | cell-based format | Scientific Literature | |
5. | ALA3118114 | B | Inhibition of ALDH3A1 in human SF-767 cells assessed as potentiation of mafosfamide-induced cytotoxicity after 19 hrs by MTT assay | Homo sapiens | 3 | ALA3112389 | cell-based format | Scientific Literature | |
6. | ALA3118115 | B | Inhibition of ALDH3A1 in human A549 cells assessed as potentiation of mafosfamide-induced cytotoxicity after 19 hrs by MTT assay | Homo sapiens | 3 | ALA3112389 | cell-based format | Scientific Literature | |
7. | ALA3118118 | B | Inhibition of ALDH3A1 in human SF-767 cells assessed as potentiation of mafosfamide-induced cytotoxicity at 10 uM after 19 hrs by MTT assay relative to control | Homo sapiens | 7 | ALA3112389 | cell-based format | Scientific Literature | |
8. | ALA3118119 | B | Inhibition of ALDH3A1 in human A549 cells assessed as potentiation of mafosfamide-induced cytotoxicity at 10 uM after 19 hrs by MTT assay relative to control | Homo sapiens | 3 | ALA3112389 | cell-based format | Scientific Literature | |
9. | ALA3118121 | B | Inhibition of recombinant ALDH3A1 (unknown origin) using benzaldehyde as substrate at 10 uM in presence of NADP+ relative to control | Homo sapiens | 8 | ALA3112389 | single protein format | Scientific Literature | |
10. | ALA3118122 | B | Inhibition of ALDH3A1 in human SF-767 cell lysate using benzaldehyde as substrate at 10 uM preincubated for 1 min followed by substrate addition in presence of NADP+ relative to control | Homo sapiens | 8 | ALA3112389 | cell-based format | Scientific Literature | |
11. | ALA3118123 | B | Inhibition of ALDH3A1 in human A549 cell lysate using benzaldehyde as substrate at 10 uM preincubated for 1 min followed by substrate addition in presence of NADP+ relative to control | Homo sapiens | 8 | ALA3112389 | cell-based format | Scientific Literature | |
12. | ALA3118126 | B | Inhibition of human wild-type ALDH3A1-mediated benzaldehyde oxidation | Homo sapiens | 1 | ALA3112389 | single protein format | Scientific Literature | |
13. | ALA3118133 | B | Non-competitive inhibition of human ALDH3A1 using benzaldehyde as substrate by Lineweaver-Burk plot analysis in presence of 100 to 500 uM NADP+ | Homo sapiens | 1 | ALA3112389 | single protein format | Scientific Literature | |
14. | ALA3118134 | B | Competitive inhibition of human ALDH3A1 using benzaldehyde as substrate by Lineweaver-Burk plot analysis in presence of 1.5 mM NADP+ | Homo sapiens | 1 | ALA3112389 | single protein format | Scientific Literature | |
15. | ALA3118331 | B | Inhibition of human ALDH3A1-mediated benzaldehyde oxidation preincubated for 1 min followed by substrate addition by spectrophotometric analysis | Homo sapiens | 24 | ALA3112389 | single protein format | Scientific Literature | |
16. | ALA3128577 | B | Inhibition of human ALDH3A1 using benzaldehyde as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 2 | ALA3124874 | single protein format | Scientific Literature | |
17. | ALA3128581 | B | Inhibition of human ALDH3A1 by Lineweaver-Burk plot analysis in presence of NADP+ | Homo sapiens | 2 | ALA3124874 | single protein format | Scientific Literature | |
18. | ALA3130564 | B | Inhibition of full length human ALDH3A1 expressed in Escherichia coli BL21 (DE3) using benzaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presence of NADP+ | Homo sapiens | 22 | ALA3124874 | assay format | Scientific Literature | |
19. | ALA3421195 | B | Inhibition of recombinant human ALDH3A1 using benzaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 1 | ALA3414499 | single protein format | Scientific Literature | |
20. | ALA3421196 | B | Inhibition of recombinant human ALDH3A1 using benzaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis | Homo sapiens | 13 | ALA3414499 | single protein format | Scientific Literature |