| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA684233 | B | Binding activity against Glucose transporter in human erythrocyte membrane using [125I]7-IHPP-Fsk as the radioligand. | 4 | cell membrane format | Scientific Literature | |||
| 2. | ALA684234 | B | Inhibition of [125I]7-IHPP-Fsk binding to glucose transporter of human erythrocyte membrane | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 3. | ALA866545 | B | Inhibitory activity against GLUT1 | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 4. | ALA2061373 | B | Inhibition of GLUT1 mediated [3H]-2-DG uptake in human LNCAP cells at 5 uM after 30 mins by scintillation counting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA2061377 | B | Inhibition of GLUT1 mediated [3H]-2-DG uptake in human LNCAP cells after 30 mins by scintillation counting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA948002 | B | Inhibition of human GLUT1-mediated 2-deoxyglucose uptake in human adipocytes at 20 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA924048 | B | Inhibition of [3H]glucose uptake at mammalian GLUT1 expressed in Xenopus laevis oocytes | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA2161764 | B | Binding affinity to recombinant GLUT1 expressed in Xenopus oocytes assessed as inhibition of [14C]glucose uptake after 20 mins by liquid scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 9. | ALA3095124 | B | Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucose addition measured after 30 mins by liquid scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA3095125 | B | Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake at 30 uM incubated for 15 mins prior to 2-deoxy-D-[3H]-glucose addition measured after 30 mins by liquid scintillation counting analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 11. | ALA2445338 | B | Induction of human myc epitope-tagged GLUT1 translocation to plasma membrane overexpressed in rat L6 cells at 25 uM after 8 hrs by immunocolorimetric analysis in presence of 23.5 mM D-glucose | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2445339 | B | Induction of human myc epitope-tagged GLUT1 translocation to plasma membrane overexpressed in rat L6 cells at 2 mM after 30 mins by immunocolorimetric analysis in presence of 23.5 mM D-glucose | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3128408 | B | Inhibition of GLUT-1 in human H1299 cells assessed as 2-deoxy-D-[3H]glucose uptake at 30 uM incubated for 15 mins prior to 2-deoxy-D-[3H]glucose challenge measured after 10 mins by liquid scintillation counting analysis (Rvb = 100%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA3436041 | F | ST_JUDE_LEISH: Cytotoxicity against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | Leishmania mexicana | 791 | assay format | St Jude Leishmania Screening | ||
| 15. | ALA3436042 | F | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | assay format | St Jude Leishmania Screening | ||
| 16. | ALA3782730 | B | Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in presence of oxidative phosphorylation inhibitor rotenone | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
| 17. | ALA3992731 | B | Inhibition of GLUT1 in human MCF7 cells assessed as reduction in [3H]-DG uptake pretreated for 20 mins followed by [3H]-DG addition measured after 6 mins by liquid scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3992733 | B | Competitive inhibition of GLUT1 in human HL60 cells assessed as reduction in 2-[1,2-3H]deoxy-D-glucose uptake measured for 30 secs by double reciprocal plot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3992734 | B | Competitive inhibition of GLUT1 (unknown origin) expressed in CHO cells assessed as reduction in 2-[1,2-3H]deoxy-D-glucose uptake measured for 30 secs by double reciprocal plot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3992735 | B | Competitive inhibition of glucose displaceable binding of [4-3H]cytochalasin B to GLUT1 in human erythrocyte membranes after 10 mins by double reciprocal plot analysis | Homo sapiens | 1 | cell membrane format | Scientific Literature |
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