# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA705239 | B | In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005) | Candida albicans | 5 | ALA1151576 | single protein format | Scientific Literature | |
2. | ALA760336 | B | In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005 (experiment 1) | Candida albicans | 1 | ALA1130883 | single protein format | Scientific Literature | |
3. | ALA762239 | B | In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005 (experiment 2) | Candida albicans | 1 | ALA1130883 | single protein format | Scientific Literature | |
4. | ALA762240 | B | In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005 | Candida albicans | 8 | ALA1130883 | single protein format | Scientific Literature | |
5. | ALA819751 | B | Binding affinity for cytochrome P450 14DM | Saccharomyces cerevisiae | 1 | ALA1126167 | single protein format | Scientific Literature | |
6. | ALA819752 | B | Binding affinity for cytochrome P450 14DM | Saccharomyces cerevisiae | 3 | ALA1126167 | single protein format | Scientific Literature | |
7. | ALA823964 | B | Inhibition of lanosterol 14-alpha-demethylase in hamster hepatic microsomes | 2 | ALA1127068 | microsome format | Scientific Literature | ||
8. | ALA824123 | B | Inhibition of lanosterol 14-alpha-demethylase in hamster hepatic microsomes | 2 | ALA1127068 | microsome format | Scientific Literature | ||
9. | ALA925158 | B | Inhibition of LDM in human HepG2 cells at 2 nM | Rattus norvegicus | 1 | ALA1140634 | cell-based format | Scientific Literature | |
10. | ALA939288 | B | Binding affinity to human His-tagged CYP51 expressed in Escherichia coli | Homo sapiens | 10 | ALA1143909 | assay format | Scientific Literature | |
11. | ALA934981 | B | Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay | Homo sapiens | 45 | ALA1143822 | cell-based format | Scientific Literature | |
12. | ALA934980 | B | Binding affinity to human reconstituted CYP51 | Homo sapiens | 1 | ALA1143822 | single protein format | Scientific Literature | |
13. | ALA934979 | B | Binding affinity to human CYP51 | Homo sapiens | 2 | ALA1143822 | single protein format | Scientific Literature | |
14. | ALA1022141 | B | Inhibition of human sterol 14-alpha-demethylase assessed as drug/enzyme molar ratio required to produce 50 percent decrease in turnover number | Homo sapiens | 6 | ALA1152782 | single protein format | Scientific Literature | |
15. | ALA1675121 | B | Binding affinity to human CYP51 | Homo sapiens | 2 | ALA1671646 | single protein format | Scientific Literature | |
16. | ALA4323740 | B | Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC analysis | Homo sapiens | 12 | ALA4321832 | assay format | Scientific Literature | |
17. | ALA4323741 | B | Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli assessed as fold change in dissociation constant incubated for 30 sec using [3H] lanosterol as substrate by HPLC analysis relative to VFV | Homo sapiens | 5 | ALA4321832 | assay format | Scientific Literature | |
18. | ALA4323742 | B | Inhibition of recombinant full length human CYP51 expressed in Escherichia coli incubated for 1 min using [3H] lanosterol as substrate by HPLC analysis | Homo sapiens | 12 | ALA4321832 | assay format | Scientific Literature | |
19. | ALA4323743 | B | Inhibition of recombinant full length human CYP51 expressed in Escherichia coli at inhibitor/enzyme ratio 50/1 incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysis relative to control | Homo sapiens | 12 | ALA4321832 | assay format | Scientific Literature | |
20. | ALA4323744 | B | Inhibition of recombinant full length human CYP51 expressed in Escherichia coli at inhibitor/enzyme ratio 25/1 incubated for 1 hr using [3H] lanosterol as substrate by HPLC analysis relative to control | Homo sapiens | 12 | ALA4321832 | assay format | Scientific Literature |