# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA641889 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture | Mus musculus | 23 | cell-based format | Scientific Literature | ||
2. | ALA641890 | B | Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay. | Mus musculus | 37 | cell-based format | Scientific Literature | ||
3. | ALA641891 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture was measured by using J774 assay; IA means inactive | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA642356 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture was measured by using J774 assay; IA means the compound was inactive | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA642357 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture was measured by using J774 assay; ND means not determined | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA642358 | B | Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture | Mus musculus | 33 | cell-based format | Scientific Literature | ||
7. | ALA643997 | B | In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 in cell culture assay using murine IC-21 macrophages at 0.1 uM | Mus musculus | 38 | single protein format | Scientific Literature | ||
8. | ALA701070 | F | Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI) | Mus musculus | 4 | assay format | Scientific Literature | ||
9. | ALA700594 | F | Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI) at 0.1 uM; not active | Mus musculus | 1 | assay format | Scientific Literature | ||
10. | ALA735446 | F | In Vitro evaluation for the CF1 liver enzyme activity on Acyl cholesterol acyltransferase at concentration 100 uM | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
11. | ALA735447 | F | In Vitro evaluation for the CF1 liver enzyme activity on Acyl cholesterol acyltransferase at concentration 200 uM | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
12. | ALA737042 | F | In Vivo effect for the hypolipidemic activity on Acyl-COA cholesterol acyltransferase in CF1 mice after 16 days of oral administration at a dose of 10 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA737043 | F | In Vivo effect for the hypolipidemic activity on Acyl-COA cholesterol acyltransferase in CF1 mice after 16 days of oral administration at a dose of 20 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA737044 | F | In Vivo effect for the hypolipidemic activity on Acyl-COA cholesterol acyltransferase in CF1 mice after 16 days of oral administration at a dose of 40 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA737045 | F | In Vivo effect for the hypolipidemic activity on Acyl-COA cholesterol acyltransferase in CF1 mice after 16 days of oral administration at a dose of 60 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA983789 | B | Inhibition of ACAT in mouse liver microsomes at 20 uM | Mus musculus | 48 | microsome format | Scientific Literature | ||
17. | ALA1267290 | B | Inhibition of ACAT mediated Wnt3a pathway activity in mouse L cell expressing Wnt3a assessed as decreased firefly luciferase reporter expression at 0.25 uM to 1 uM | Mus musculus | 1 | cell-based format | Scientific Literature | ||
18. | ALA3882624 | B | Inhibition of ACAT1 in mouse N9 cells | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
19. | ALA3882625 | B | Inhibition of ACAT1 in mouse N9 cells assessed as reduction in oligomeric amyloid beta 1 to 42 pretreated for 24 hrs followed by oligomeric amyloid beta 1 to 42 addition measured after 12 hrs by Western blot analysis relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
20. | ALA3882626 | B | Inhibition of ACAT1 in wild type mouse microglia assessed as increase in clearance of oligomeric amyloid beta at 1 uM pretreated for 24 hrs followed by oligomeric amyloid beta addition measured after 18 hrs by western blot analysis relative to control | Mus musculus | 1 | single protein format | Patent Bioactivity Data |