| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA695889 | B | Inhibitory activity against histone deacetylase 6 prepared from mouse melanoma B16/BL6 cells | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA925326 | B | Inhibition of mouse HDAC6 expressed in 293T cells | Mus musculus | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA898811 | B | Inhibition of mouse recombinant HDAC6 expressed in 293 cells | Mus musculus | 19 | cell-based format | Scientific Literature | ||
| 4. | ALA1680280 | B | Inhibition of HDAC6 in mouse primary forebrain neurons assessed as acetylation of tubulin at 92.5 uM after 24 hrs by immunofluorescence assay | Mus musculus | 2 | assay format | Scientific Literature | ||
| 5. | ALA2188466 | B | Inhibition of HDAC6 in mouse B16 cells assessed as increase in acetyl alpha-tubulin level incubated for 24 hrs by Western blotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2318095 | B | Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assay | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 7. | ALA3129508 | B | Inhibition of mouse HDAC6 expressed in human 293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA3366594 | B | Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader | Mus musculus | 7 | single protein format | Scientific Literature | ||
| 9. | ALA3366599 | B | Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreitol | Mus musculus | 7 | single protein format | Scientific Literature | ||
| 10. | ALA3368834 | B | Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIPR method | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA4004574 | B | Inhibition of HDAC6 in mouse B16F10 cells assessed as accumulation of acetylated tubulin at 20 uM after 24 hrs by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4004575 | B | Inhibition of HDAC6 in mouse B16F10 cells assessed as accumulation of acetylated tubulin at 5 to 50 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4004576 | B | Inhibition of HDAC6 in mouse B16F10 cells assessed as accumulation of acetylated tubulin after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4041755 | B | Inhibition of mouse FLAG-tagged HDAC6 expressed in human 293T cells coexpressing HDA2 up to 50 uM using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4135549 | B | Inhibition of HDAC6 in C57BL/6 mouse primary peritoneal macrophages assessed as decrease in IL-10 production at 3 uM after 24 hrs by ELISA | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4135550 | B | Inhibition of HDAC6 in mouse RAW264.7 cells assessed as decrease in IL-10 production at 3 uM after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4198929 | B | Inhibition of HDAC6 in Tg2576 mouse primary neurons assessed as reduction in human APP protein level at 100 nM treated for 2 days measured at 24 hrs post last dose by Western blot analysis relative to control | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4198930 | B | Inhibition of HDAC6 in Tg2576 mouse primary neurons assessed as reduction in phosphorylated tau protein level at 100 nM treated for 2 days measured at 24 hrs post last dose by Western blot analysis relative to control | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4199460 | B | Inhibition of HDAC6 in mouse Neuro-2a cells transfected with pCAX FLAG APP and pRK5-EGFP-Tau P301L plasmids assessed as inhibition of Tau P301L mutant phosphorylation at Ser396 residue at 1 uM after 24 hrs by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4199461 | B | Inhibition of HDAC6 in mouse Neuro-2a cells transfected with pCAX FLAG APP and pRK5-EGFP-Tau P301L plasmids assessed as inhibition of Tau P301L mutant phosphorylation at Ser404 residue at 1 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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