| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA706597 | B | Inhibitory activity against Leucine aminopeptidase | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2033149 | B | Activity of leucine aminopeptidase after 2.5 hrs by spectrophotometry | 1 | single protein format | Scientific Literature | |||
| 3. | ALA936433 | B | Inhibition of human recombinant IRAP expressed in HEK293 cells | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 4. | ALA948330 | B | Displacement of [125I]Angiotensin 4 from human recombinant IRAP expressed in CHOK1 cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA948331 | B | Inhibition of human recombinant IRAP expressed in HEK293 cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 6. | ALA1100890 | B | Inhibition of catalytic activity of human IRAP transfected in HEK293 cells assessed as formation of p-nitroaniline | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 7. | ALA1286213 | B | Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1,10-Phe | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA1286214 | B | Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,10-Phe | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 9. | ALA1286215 | B | Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 10. | ALA1286217 | B | Ratio of compound Ki to angiotensin 4 Ki for human recombinant IRAP expressed in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA1787846 | B | Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as cleavage of substrate L-leucine-p-nitroanilide to L-leucine and p-nitroaniline measured every 5 mins for 10 to 50 mins by spectrophotometric analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 12. | ALA2422391 | B | Inhibition of human recombinant IRAP expressed in HeLa cells assessed as L-Leucine-7-amido-4-methyl coumarin hydrolysis to 7-amido-4-methyl coumarin at 50 to 100 uM after 5 to 10 mins by fluorescence assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA2422395 | B | Inhibition of human recombinant IRAP expressed in HeLa cells assessed as L-Leucine-7-amido-4-methyl coumarin hydrolysis to 7-amido-4-methyl coumarin after 5 to 10 mins by fluorescence assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 14. | ALA3130959 | B | Inhibition of IRAP in HEKT cells assessed as hydrolysis of L-leucine-4-methyl-7-coumarinylamide after 30 mins | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 15. | ALA3130960 | B | Inhibition of IRAP in HEKT cells assessed as hydrolysis of L-leucine-4-methyl-7-coumarinylamide at 100 uM after 30 mins relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 16. | ALA3418222 | B | Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as substrate up to 100 uM after 5 to 10 mins by fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 17. | ALA3419982 | B | Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay | Homo sapiens | 68 | cell-based format | Scientific Literature | ||
| 18. | ALA3420177 | B | Inhibition of IRAP (unknown origin) expressed in CHO cells using L--leucine-p-nitroanilide as substrate after 6 to 12 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4011377 | B | Inhibition of recombinant human IRAP expressed in GnT1 deficient HEK293S cells using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4024807 | B | Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assay | Homo sapiens | 31 | cell-based format | Scientific Literature |
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