# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA710255 | B | Concentration required for half maximal activity was calculated in human nuclear oxysterol receptor liver X receptor-alpha in LiSA. | 14 | ALA1134370 | assay format | Scientific Literature | ||
2. | ALA710256 | B | Ligand-dependent recruitment of steroid receptor co-activator 1 (SRC1) to Liver X receptor-alpha | Homo sapiens | 12 | ALA1135404 | single protein format | Scientific Literature | |
3. | ALA710257 | B | Effective concentration in LXR alpha-Gal4 receptor gene assay | Homo sapiens | 10 | ALA1135404 | single protein format | Scientific Literature | |
4. | ALA710258 | B | Effective concentration in LXR alpha-Gal4 receptor gene assay; inactive at 10 uM | Homo sapiens | 1 | ALA1135404 | single protein format | Scientific Literature | |
5. | ALA710259 | B | Binding affinity towards LXR alpha receptor was determined in LiSA | 1 | ALA1134370 | single protein format | Scientific Literature | ||
6. | ALA712587 | B | Effective concentration in LXR alpha-Gal4 receptor gene assay; Not tested | Homo sapiens | 1 | ALA1135404 | single protein format | Scientific Literature | |
7. | ALA712588 | F | Relative efficacy compared to 24(S),25-epoxy cholesterol in LXR alpha-Gal4 receptor gene assay | Homo sapiens | 1 | ALA1135404 | assay format | Scientific Literature | |
8. | ALA712589 | F | Relative efficacy compared to 24(S),25-epoxy cholesterol in LXR alpha-Gal4 receptor gene assay | Homo sapiens | 10 | ALA1135404 | assay format | Scientific Literature | |
9. | ALA712590 | F | Relative efficacy compared to 24(S),25-epoxy cholesterol in Liver X receptor-alpha ligand-sensing assay | Homo sapiens | 12 | ALA1135404 | assay format | Scientific Literature | |
10. | ALA712591 | B | Tested for its ability to activate Liver X receptor-alpha expressed as Relative efficacy determined by maximal increase in relative fluorescence in LiSA | 19 | ALA1134370 | single protein format | Scientific Literature | ||
11. | ALA712592 | B | Tested for its ability to activate Liver X receptor-alpha expressed as Relative efficacy determined by maximal increase in relative fluorescence in LiSA by 100 uM | 1 | ALA1134370 | single protein format | Scientific Literature | ||
12. | ALA828306 | B | Relative efficacy for Steroid receptor coactivator-1 (SRC1) recruitment to human LXRalpha compared to GW-3965 | Homo sapiens | 11 | ALA1145169 | single protein format | Scientific Literature | |
13. | ALA841800 | B | Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assay | Homo sapiens | 5 | ALA1145279 | cell-based format | Scientific Literature | |
14. | ALA829882 | B | Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assay; Not tested | Homo sapiens | 4 | ALA1145279 | cell-based format | Scientific Literature | |
15. | ALA830107 | B | Effective concentration for cofactor association with recombinant liver X receptor-alpha | Homo sapiens | 7 | ALA1145279 | assay format | Scientific Literature | |
16. | ALA829289 | B | Effective concentration for Steroid receptor coactivator-1 (SRC1) recruitment to human LXRalpha (Liver X receptor) | Homo sapiens | 11 | ALA1145169 | single protein format | Scientific Literature | |
17. | ALA839786 | B | Effective concentration for cofactor association with recombinant liver X receptor-alpha; Not active | Homo sapiens | 2 | ALA1145279 | assay format | Scientific Literature | |
18. | ALA839787 | B | Effective concentration for cofactor association with recombinant liver X receptor-alpha; Not tested | Homo sapiens | 2 | ALA1145279 | assay format | Scientific Literature | |
19. | ALA832531 | B | Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assay; not calculated as plateau not reached at doses tested | Homo sapiens | 1 | ALA1145279 | cell-based format | Scientific Literature | |
20. | ALA829561 | B | Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assay | Homo sapiens | 3 | ALA1145279 | assay format | Scientific Literature |