| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA711709 | F | Tested in vitro against human recombinant Metabotropic glutamate receptor 5 stably expressed in LtK cells by [Ca2+] flux assay using glutamate as antagonist | 8 | cell-based format | Scientific Literature | |||
| 2. | ALA711710 | B | Tested in vitro binding affinity for displacement of [3H]M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, activity expressed as IC50 | 3 | assay format | Scientific Literature | |||
| 3. | ALA711711 | F | Agonistic activity against Human Metabotropic glutamate receptor 5 at 1 uM concentration; no inhibition | 1 | assay format | Scientific Literature | |||
| 4. | ALA711712 | F | Agonist potency against cloned metabotropic glutamate receptor 5 | 45 | assay format | Scientific Literature | |||
| 5. | ALA711713 | B | Phosphoinositide hydrolysis by human Metabotropic glutamate receptor 5 (mGluR5) expressed in non-neuronal cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA709915 | F | Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5) | 2 | assay format | Scientific Literature | |||
| 7. | ALA709916 | B | Compound was tested for the inhibition of Metabotropic glutamate receptor 5 | 3 | single protein format | Scientific Literature | |||
| 8. | ALA709917 | F | The compound was tested for effect on second messenger formation in BHK cells expressing mGluR5a | 2 | cell-based format | Scientific Literature | |||
| 9. | ALA709918 | F | The compound was tested for effect on second messenger formation in BHK cells expressing mGluR5a at half maximal concentration | 1 | cell-based format | Scientific Literature | |||
| 10. | ALA709919 | F | Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5) | 2 | assay format | Scientific Literature | |||
| 11. | ALA718125 | F | The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR5a | 2 | cell-based format | Scientific Literature | |||
| 12. | ALA880764 | B | Compound was tested for the inhibition of Metabotropic glutamate receptor 5 | 4 | single protein format | Scientific Literature | |||
| 13. | ALA712881 | F | Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluated | 10 | assay format | Scientific Literature | |||
| 14. | ALA711155 | F | Compound (300 uM) was evaluated for percentage agonist activity against human mGluR5 expressed in chinese hamster ovary cells | 1 | cell-based format | Scientific Literature | |||
| 15. | ALA715719 | B | Activity against human Metabotropic glutamate receptor 5 up to a concentration of 300 uM; Not active | 1 | single protein format | Scientific Literature | |||
| 16. | ALA715720 | B | Phosphoinositide hydrolysis by Metabotropic glutamate receptor 5 (mGluR5) expressed in non neuronal cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA715721 | B | Phosphoinositide hydrolysis by human Metabotropic glutamate receptor 5 (mGluR5) expressed in non neuronal cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 18. | ALA715722 | B | Phosphoinositide hydrolysis by human Metabotropic glutamate receptor 5 (mGluR5) expressed in non neuronal cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA715723 | B | Concentration for half maximal activation of metabotropic glutamate mGluR5a in human | 2 | single protein format | Scientific Literature | |||
| 20. | ALA715724 | B | Binding affinity towards human mGlu5 receptors expressed in LtK-cells | 2 | cell-based format | Scientific Literature |
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