| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA712467 | B | Inhibition of c-AMP by human Metabotropic glutamate receptor 8 (mGluR8) expressed in non-neuronal cells | Homo sapiens | 1 | ALA1135971 | cell-based format | Scientific Literature | |
| 2. | ALA712468 | B | Inhibition of c-AMP by human Metabotropic glutamate receptor 8 (mGluR8) expressed in non-neuronal cells | Homo sapiens | 7 | ALA1135971 | cell-based format | Scientific Literature | |
| 3. | ALA712469 | B | Inhibition of c-AMP by human Metabotropic glutamate receptor 8 (mGluR8) expressed in non-neuronal cells | Homo sapiens | 1 | ALA1135971 | cell-based format | Scientific Literature | |
| 4. | ALA712470 | F | In vitro antagonist activity at recombinant Metabotropic glutamate receptor 8 expressed in RGT cells. | 12 | ALA1130904 | cell-based format | Scientific Literature | ||
| 5. | ALA712471 | F | In vitro antagonist activity at recombinant Metabotropic glutamate receptor 8 expressed in RGT cells; Not tested. | 11 | ALA1130904 | cell-based format | Scientific Literature | ||
| 6. | ALA712472 | F | Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 8 by measuring L-AP4 (0.3 uM of forskolin) (15 uM)-stimulated cAMP formation | 2 | ALA1131280 | cell-based format | Scientific Literature | ||
| 7. | ALA712473 | F | Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8). | 18 | ALA1133464 | assay format | Scientific Literature | ||
| 8. | ALA709835 | B | Inhibition of c-AMP by human Metabotropic glutamate receptor 8 (mGluR8) expressed in non-neuronal cells | Homo sapiens | 4 | ALA1135971 | cell-based format | Scientific Literature | |
| 9. | ALA712883 | F | Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated | 10 | ALA1130627 | assay format | Scientific Literature | ||
| 10. | ALA824614 | F | Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR8 | 3 | ALA1132607 | cell-based format | Scientific Literature | ||
| 11. | ALA828854 | B | Dissociation constant of radiolabeled compound against recombinant human Metabotropic glutamate receptor 8 | Homo sapiens | 1 | ALA1142833 | single protein format | Scientific Literature | |
| 12. | ALA840003 | B | Maximum number of binding sites on recombinant human Metabotropic glutamate receptor 8 | Homo sapiens | 1 | ALA1142833 | single protein format | Scientific Literature | |
| 13. | ALA828593 | B | Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8 | Homo sapiens | 2 | ALA1142833 | single protein format | Scientific Literature | |
| 14. | ALA865707 | B | Activity against mGluR8 | Homo sapiens | 2 | ALA1146979 | single protein format | Scientific Literature | |
| 15. | ALA856309 | F | Activity at human mGluR8 assessed as inhibition of glutamate-induced calcium influx by FLIPR assay | Homo sapiens | 2 | ALA1149355 | assay format | Scientific Literature | |
| 16. | ALA912291 | F | Agonist activity at human mGluR8 assessed as effect on cAMP production in RGT cells | Homo sapiens | 5 | ALA1139833 | cell-based format | Scientific Literature | |
| 17. | ALA888779 | B | Binding affinity at mGluR8 | 1 | ALA1145430 | single protein format | Scientific Literature | ||
| 18. | ALA890721 | F | Agonist activity at mGlu8 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production | 5 | ALA1146221 | cell-based format | Scientific Literature | ||
| 19. | ALA890724 | F | Agonist activity at mGlu8 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production relative to 2-amino-4-phosphonobutyric acid | 1 | ALA1146221 | cell-based format | Scientific Literature | ||
| 20. | ALA948795 | F | Antagonist activity at mGluR8 assessed as effect on glutamate-induced response | 1 | ALA1143275 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!