# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA681450 | F | Compound was tested for its ability to inhibit uptake of [3H]- GABA by cloned human GAT-1 transporter | 5 | ALA1129108 | assay format | Scientific Literature | ||
2. | ALA806333 | B | Inhibitory activity against human GABA transporter-1 (hGAT1) | 28 | ALA1127589 | single protein format | Scientific Literature | ||
3. | ALA881972 | B | Percent inhibition against GABA transporter at a compound concentration of 1 uM | Homo sapiens | 3 | ALA1140374 | single protein format | Scientific Literature | |
4. | ALA862288 | B | Inhibition of GAT1 transport activity | Homo sapiens | 22 | ALA1148561 | single protein format | Scientific Literature | |
5. | ALA1166723 | B | Binding affinity to GAT1 | 3 | ALA1165889 | single protein format | Scientific Literature | ||
6. | ALA1647445 | B | Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assay | Homo sapiens | 52 | ALA1641586 | cell-based format | Scientific Literature | |
7. | ALA1663477 | B | Inhibition of [3H]GABA uptake at GAT1 expressed in HEK cells | 18 | ALA1649378 | cell-based format | Scientific Literature | ||
8. | ALA1663478 | B | Inhibition of [3H]GABA uptake at GAT1 expressed in HEK cells at 100 uM | 1 | ALA1649378 | cell-based format | Scientific Literature | ||
9. | ALA1776005 | B | Inhibition of human GAT1-mediated GABA uptake | Homo sapiens | 1 | ALA1773002 | single protein format | Scientific Literature | |
10. | ALA1918360 | B | Inhibition of human GAT1 assessed as [3H]GABA uptake | Homo sapiens | 1 | ALA1914421 | single protein format | Scientific Literature | |
11. | ALA2208544 | B | Inhibition of human GAT1 expressed in tcA201 cells assessed as inhibition of [3H]GABA uptake at 1 mM after 3 mins by scintillation counting | Homo sapiens | 1 | ALA2203122 | cell-based format | Scientific Literature | |
12. | ALA2405421 | B | Inhibition of GABA uptake at GAT-1 (unknown origin) | Homo sapiens | 3 | ALA2401667 | single protein format | Scientific Literature | |
13. | ALA2417030 | B | Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | Homo sapiens | 5 | ALA2413054 | cell-based format | Scientific Literature | |
14. | ALA2417034 | B | Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake at 100 uM after 20 mins by liquid scintillation counting analysis | Homo sapiens | 8 | ALA2413054 | cell-based format | Scientific Literature | |
15. | ALA2432985 | B | Activity at GAT1 (unknown origin) expressed in african green monkey COS7 cells assessed as GABA release at 0.5 to 500 uM after 10 mins using [3H]-GABA pretreated for 1 hr before compound addition followed by wash out by reversed transport efflux assay | Homo sapiens | 1 | ALA2429840 | cell-based format | Scientific Literature | |
16. | ALA2432988 | B | Allosteric modulation of GAT-1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate at 20 uM | Homo sapiens | 1 | ALA2429840 | cell-based format | Scientific Literature | |
17. | ALA2432991 | B | Non-competitive inhibition of GAT-1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate | Homo sapiens | 1 | ALA2429840 | cell-based format | Scientific Literature | |
18. | ALA2433117 | B | Inhibition of GAT-1 (unknown origin) | Homo sapiens | 3 | ALA2429840 | single protein format | Scientific Literature | |
19. | ALA2433118 | B | Inhibition of GAT-1 (unknown origin) expressed in african green monkey COS7 cells using [3H]-GABA as substrate after 10 mins by scintillation counting | Homo sapiens | 1 | ALA2429840 | cell-based format | Scientific Literature | |
20. | ALA3363226 | B | Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | Homo sapiens | 4 | ALA3351485 | cell-based format | Scientific Literature |