# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869059 | B | Inhibition of human spleen HO1 | Homo sapiens | 1 | ALA1138063 | single protein format | Scientific Literature | |
2. | ALA1035716 | B | Inhibition of human recombinant HO1 expressed in Escherichia coli DH5alpha assessed as heme degradation at 25 uM by spectrophotometry in presence of L-ascorbic acid relative to control | Homo sapiens | 1 | ALA1140121 | assay format | Scientific Literature | |
3. | ALA1035717 | B | Inhibition of human recombinant HO1 expressed in Escherichia coli DH5alpha assessed as heme degradation at 10 uM by spectrophotometry in presence of L-ascorbic acid relative to control | Homo sapiens | 1 | ALA1140121 | assay format | Scientific Literature | |
4. | ALA1036575 | B | Inhibition of human recombinant HO1 expressed in Escherichia coli DH5alpha assessed as heme degradation at 25 uM by spectrophotometry in absence of L-ascorbic acid relative to control | Homo sapiens | 2 | ALA1140121 | assay format | Scientific Literature | |
5. | ALA1036576 | B | Inhibition of human recombinant HO1 expressed in Escherichia coli DH5alpha assessed as heme degradation at 50 uM by spectrophotometry in absence of L-ascorbic acid relative to control | Homo sapiens | 2 | ALA1140121 | assay format | Scientific Literature | |
6. | ALA3418068 | A | Effect on heme oxygenase-1 (unknown origin)-mediated HCV replication in human MH14 cells transfected with pHO-1-Luc by luciferase reporter gene assay | Homo sapiens | 1 | ALA3414521 | cell-based format | Scientific Literature | |
7. | ALA3625265 | B | Inhibition of heme oxygenase-1 (unknown origin) | Homo sapiens | 1 | ALA3621085 | single protein format | Scientific Literature | |
8. | ALA4143858 | B | Induction of HO-1-mediated reduction on HCV NS3/4A protease activity in human Huh-7 cells transfected with pEG(DE4AB)SEAP/pNS3/4A after 3 days | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
9. | ALA4143859 | B | Induction of HO-1-mediated ISRE promoter activity in human Ava5 cells transfected with pISRE-Luc after 3 days | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
10. | ALA4143860 | B | Induction of HO-1-mediated IFN-alpha-2 mRNA expression in human Ava5 cells after 3 days by RT-qPCR method | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
11. | ALA4143861 | B | Induction of HO-1-mediated IFN-alpha-5 mRNA expression in human Ava5 cells after 3 days by RT-qPCR method | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
12. | ALA4143862 | B | Induction of HO-1-mediated IFN-alpha-17 mRNA expression in human Ava5 cells after 3 days by RT-qPCR method | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
13. | ALA4143863 | B | Induction of HO-1-mediated OAS1 mRNA expression in human Ava5 cells after 3 days by RT-qPCR method | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
14. | ALA4143864 | B | Induction of HO-1-mediated OAS3 mRNA expression in human Ava5 cells after 3 days by RT-qPCR method | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
15. | ALA4143865 | B | Induction of HO-1-mediated PKR mRNA expression in human Ava5 cells after 3 days by RT-qPCR method | Homo sapiens | 1 | ALA4138248 | cell-based format | Scientific Literature | |
16. | ALA4268725 | B | Inhibition of heme oxygenase 1 in human K562R cell lysates assessed as decrease in bilirubin formation at 10 uM after 60 mins by spectrophotometric method | Homo sapiens | 5 | ALA4265959 | single protein format | Scientific Literature | |
17. | ALA4268726 | B | Inhibition of heme oxygenase 1 in human K562R cells assessed as decrease in HO-1 mRNA levels at 10 uM by qRT-PCR method | Homo sapiens | 3 | ALA4265959 | cell-based format | Scientific Literature | |
18. | ALA4433398 | B | Inhibition of human recombinant HO-1 by spectrometry based assay | Homo sapiens | 5 | ALA4433201 | single protein format | Scientific Literature | |
19. | ALA5056455 | B | Inhibition of human HO-1 activity in human U-87MG cells assessed as bilirubin formation at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA5055640 | cell-based format | Scientific Literature | |
20. | ALA5056456 | B | Inhibition of human HO-1 activity in human U-87MG cells assessed as reduction in immunoreactivity in cytoplasm at 10 uM incubated for 48 hrs by DAPI staining analysis | Homo sapiens | 1 | ALA5055640 | cell-based format | Scientific Literature |