| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1687116 | B | Effect on NFATc1 in HEK293 nuclear extract at 50 uM after 15 mins by EMSA assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA3861320 | B | Reduction in NFATc1 nuclear localization in human anti-CD3/anti-CD28 stimulated Jurkat T cells at 10 ug measured after 15 mins by SDS-PAGE and immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4034243 | B | Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI staining based assay | Homo sapiens | 33 | assay format | Scientific Literature | ||
| 4. | ALA4824774 | B | Inhibition of human NFAT-1 in human Jurkat cells assessed as decrease of PMA/ionomycin-induced NFAT dephosphorylation at 15 uM measured after 44 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4824777 | B | Inhibition of human NFAT-1 in human Jurkat cells assessed as decrease of PMA/ionomycin-induced NFAT dephosphorylation measured after 44 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4824778 | B | Inhibition of human NFAT-1 in human Jurkat cells assessed as decrease of PMA/ionomycin-induced IL-2 concentration measured after 44 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4824779 | B | Inhibition of human NFAT-1 in human Jurkat cells assessed as decrease of PMA/ionomycin-induced IL-2 concentration at 15 uM measured after 44 hrs by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5129610 | B | Inhibition of NFATC activity in HEK293T cells at 5 to 50 uM preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 9. | ALA5129611 | B | Inhibition of NFATC activity in HEK293T cells at 50 uM preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 10. | ALA5129612 | B | Inhibition of NFATC activity in HEK293T cells preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA5129614 | B | Inhibition of NFATC activity in human PBMC cells assessed as reduction of IL2 gene expression preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA5129615 | B | Inhibition of NFATC activity in human PBMC cells assessed as reduction of IFN gamma gene expression preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs byRT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA5129616 | B | Inhibition of NFATC activity in human CD4+ T cells assessed as reduction of IFN gamma secretion preincubated for 2 hrs followed by anti-CD3/CD28 stimulation and measured after 48 hrs by ELISA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA5129617 | B | Inhibition of NFATC activity in human CD4+ T cells assessed as reduction of IL-2 secretion preincubated for 2 hrs followed by anti-CD3/CD28 stimulation and measured after 48 hrs by ELISA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA5136269 | B | Induction of NFATC1 degradation in human MINO cells at 100 nM measured after 8 hrs by proteomic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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