| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1794323 | Functional | PUBCHEM_BIOASSAY: SAR analysis of small molecule inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493160, AID493190] | 43 | ALA1201862 | assay format | PubChem BioAssays | ||
| 2. | ALA1794477 | Functional | PUBCHEM_BIOASSAY: SAR analysis of small molecule inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493160, AID493190] | 89 | ALA1201862 | assay format | PubChem BioAssays | ||
| 3. | ALA1738619 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493187, AID493207] | Homo sapiens | 101 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA2166286 | Binding | Activation of human hexokinase 1 at 500 times EC50 concentration | Homo sapiens | 1 | ALA2163316 | single protein format | Scientific Literature | |
| 5. | ALA2318451 | Binding | Induction of hexokinase 1 (unknown origin) | Homo sapiens | 1 | ALA2311350 | single protein format | Scientific Literature | |
| 6. | ALA3578773 | Binding | Effect on hexokinase-1 (unknown origin) | Homo sapiens | 1 | ALA3576833 | single protein format | Scientific Literature | |
| 7. | ALA3807033 | Binding | Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo assay in presence of MgATP | Homo sapiens | 25 | ALA3804808 | assay format | Scientific Literature | |
| 8. | ALA5167810 | Binding | Binding affinity to hexokinase-1 in human MCF7 cell lysate assessed as HK-1 pull down by western blotting based Co-immunoprecipitation assay | Homo sapiens | 1 | ALA5154927 | subcellular format | Scientific Literature | |
| 9. | ALA5167824 | Binding | Binding affinity to hexokinase-1 in human MCF7 cell lysate measured after overnight incubation by LC-MS/MS analysis | Homo sapiens | 1 | ALA5154927 | subcellular format | Scientific Literature | |
| 10. | ALA5167825 | Binding | Inhibition of human recombinant hexokinase-1 assessed as NADPH generation measured after 1 hr by HPLC analysis | Homo sapiens | 1 | ALA5154927 | single protein format | Scientific Literature |
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