# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA655540 | F | Modulation of Pgp (P-glycoprotein) mediated multidrug resistance in CEM / VLB 1000 cell line | Homo sapiens | 27 | ALA1132822 | cell-based format | Scientific Literature | |
2. | ALA653300 | F | Evaluated for inhibition of growth of CEM/VLB1000 cell line using multidrug resistance (MDR) potentiation assay | Homo sapiens | 26 | ALA1132821 | cell-based format | Scientific Literature | |
3. | ALA695682 | F | In vitro for its inhibitory activity against MRP1-transfected HeLa-T5 cell line in the presence of doxorubicin | Homo sapiens | 23 | ALA1135242 | cell-based format | Scientific Literature | |
4. | ALA700941 | F | Pgp transport inhibitory activity at 1 uM was measured by JC-1 accumulation assay method using JC-1 as substrate | 28 | ALA1132167 | assay format | Scientific Literature | ||
5. | ALA700942 | F | Pgp transport inhibitory activity at 10 uM was measured by JC-1 accumulation assay method using JC-1 as substrate | 28 | ALA1132167 | assay format | Scientific Literature | ||
6. | ALA700943 | F | Pgp transport inhibitory activity at 5 uM was measured by JC-1 accumulation assay method using JC-1 as substrate | 27 | ALA1132167 | assay format | Scientific Literature | ||
7. | ALA710067 | B | Human MDR1 Pgp inhibitory activity by using standard calcein-AM efflux method with the human leukemia CEM cells. | 26 | ALA1133762 | cell-based format | Scientific Literature | ||
8. | ALA710068 | B | Human MDR1 Pgp inhibitory activity by using standard calcein-AM efflux method with the human leukemia CEM cells. | 26 | ALA1133762 | cell-based format | Scientific Literature | ||
9. | ALA754774 | B | Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affinity model | Cricetulus griseus | 12 | ALA1135688 | single protein format | Scientific Literature | |
10. | ALA755180 | B | Concentration required for 50% inhibition (racemic) at binding site of human P-Glycoprotein (P-gp) in one-affinity model | 1 | ALA1135688 | single protein format | Scientific Literature | ||
11. | ALA755181 | B | Concentration required for 50% inhibition at binding site of human P-Glycoprotein (P-gp) in one-affinity model | 15 | ALA1135688 | single protein format | Scientific Literature | ||
12. | ALA755182 | B | Inhibitory activity against Human MDR1 P-Glycoprotein ABC Transporter using leukemia CEM cells | 59 | ALA1135619 | cell-based format | Scientific Literature | ||
13. | ALA755183 | B | Inhibitory activity against Human MDR1 P-Glycoprotein ABC Transporter using leukemia CEM cells; NA is No IC50 value achievable | 1 | ALA1135619 | cell-based format | Scientific Literature | ||
14. | ALA753510 | B | High affinity constant at binding site of human P-Glycoprotein (P-gp) in two-affinity model | 11 | ALA1135688 | single protein format | Scientific Literature | ||
15. | ALA753511 | B | Fraction of high affinity at binding site of human P-Glycoprotein (P-gp) in two-affinity model | 11 | ALA1135688 | single protein format | Scientific Literature | ||
16. | ALA755826 | F | Inhibition of P-glycoprotein using ATPase in MDR1 membranes | 28 | ALA1136781 | cell membrane format | Scientific Literature | ||
17. | ALA755827 | F | Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay | 28 | ALA1136781 | cell-based format | Scientific Literature | ||
18. | ALA754160 | F | Inhibition of P-glycoprotein using calcein-AM assay transfected in porcine PBCEC | 28 | ALA1136781 | assay format | Scientific Literature | ||
19. | ALA754161 | F | Inhibition of P-gp was determined using rhodamine-assay in human CaCo-2 cells | 28 | ALA1136781 | cell-based format | Scientific Literature | ||
20. | ALA751609 | F | Compound was evaluated for broad range of antagonistic activity against P-glycoprotein (Pgp) value expressed as IC20 | 10 | ALA1149323 | assay format | Scientific Literature |