# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA666972 | Binding | Percent binding affinity against dopamine D3 receptor | Rattus norvegicus | 1 | ALA1146741 | single protein format | Scientific Literature | |
2. | ALA666975 | Binding | Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone); NA means inactive | 1 | ALA1150496 | cell-based format | Scientific Literature | ||
3. | ALA666976 | Binding | Binding affinity was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone); NT means not tested | 2 | ALA1150496 | cell-based format | Scientific Literature | ||
4. | ALA666977 | Binding | Percent inhibition against dopamine D3 receptor at a concentration of 1 umol/L | 1 | ALA1150496 | single protein format | Scientific Literature | ||
5. | ALA666978 | Functional | Antagonistic activity at D3 receptor using in vitro functional assay | 1 | ALA1134827 | assay format | Scientific Literature | ||
6. | ALA671914 | Binding | Affinity on C6 glioma cells transfected with Dopamine receptor D3 | Rattus norvegicus | 11 | ALA1132603 | cell-based format | Scientific Literature | |
7. | ALA673250 | Binding | Tested for in vitro binding affinity against cloned mammalian dopamine autoreceptor, expressed in CHO-K1 cells, using [3H]spiperone as radioligand | 1 | ALA1127438 | cell-based format | Scientific Literature | ||
8. | ALA679085 | Functional | Antagonist activity by measuring the inhibition of quinpirole stimulated [3H]- thymidine uptake against Dopamine receptor D3; NA means Not Active | 1 | ALA1133458 | assay format | Scientific Literature | ||
9. | ALA678232 | Functional | Antagonist activity by measuring the inhibition of quinpirole stimulated [3H]- thymidine uptake against Dopamine receptor D3; the compound is active | 2 | ALA1133458 | assay format | Scientific Literature | ||
10. | ALA678233 | Functional | Maximal stimulation reached was evaluated by using [35S]- GTP-gamma S radioligand | 1 | ALA1145068 | assay format | Scientific Literature | ||
11. | ALA678234 | Binding | Saturable binding was tested dopamine receptor D3 in rat striatal membrane homogenate | 1 | ALA1126578 | cell membrane format | Scientific Literature | ||
12. | ALA678235 | Functional | Agonist activity by measuring the [3H]-thymidine uptake against Dopamine receptor D3 from rat | 1 | ALA1133458 | assay format | Scientific Literature | ||
13. | ALA678236 | Functional | Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D3 from rat | 3 | ALA1133458 | assay format | Scientific Literature | ||
14. | ALA678237 | Binding | Basal binding towards Dopamine receptor D3 was evaluated using [35S]- GTP-gamma S radioligand | 1 | ALA1145068 | single protein format | Scientific Literature | ||
15. | ALA678238 | Functional | Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay | 2 | ALA1133651 | cell-based format | Scientific Literature | ||
16. | ALA678239 | Functional | Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay (intrinsic activity) | 2 | ALA1133651 | cell-based format | Scientific Literature | ||
17. | ALA678240 | Binding | Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatum | 4 | ALA1136809 | tissue-based format | Scientific Literature | ||
18. | ALA678241 | Binding | Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatum. | 1 | ALA1136809 | tissue-based format | Scientific Literature | ||
19. | ALA678242 | Binding | Inhibitory concentration against [3H]spiperone binding to Dopamine receptor D3 expressed in CHO-K1 cells | Rattus norvegicus | 8 | ALA1159176 | cell-based format | Scientific Literature | |
20. | ALA678243 | Binding | relative affinity against Dopamine receptor D3 in ventral striatum using [3H](+)-7-OH-DPAT as radioligand | 7 | ALA1131617 | tissue-based format | Scientific Literature |