# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA754356 | B | Evaluated for binding affinity by inhibiting binding of [125I]Tyr(3)-NT to human Neurotensin receptor 3 | 21 | ALA1145090 | single protein format | Scientific Literature | ||
2. | ALA2405877 | B | Binding affinity to NTR3 (unknown origin) | Homo sapiens | 1 | ALA2401662 | single protein format | Scientific Literature | |
3. | ALA3100564 | B | Displacement of [3H]-neurotensin from human sortilin incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintillation proximity assay | Homo sapiens | 1 | ALA3098109 | single protein format | Scientific Literature | |
4. | ALA3100580 | B | Displacement of [3H]-neurotensin from sortilin (unknown origin) at 50 uM incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintillation proximity assay | Homo sapiens | 11 | ALA3098109 | single protein format | Scientific Literature | |
5. | ALA3100581 | B | Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintillation proximity assay | Homo sapiens | 20 | ALA3098109 | single protein format | Scientific Literature | |
6. | ALA4030310 | B | Displacement of [3H]-neurotensin from human His6-tagged sortilin pretreated for 30 mins followed by [3H]-neurotensin addition after 6 hrs measured for 360 secs by SPA | Homo sapiens | 20 | ALA4028841 | single protein format | Scientific Literature | |
7. | ALA4030311 | B | Displacement of [3H]-neurotensin from human His6-tagged sortilin at 500 uM pretreated for 30 mins followed by [3H]-neurotensin addition after 6 hrs measured for 360 secs by SPA relative to control | Homo sapiens | 21 | ALA4028841 | single protein format | Scientific Literature | |
8. | ALA4629041 | B | Inhibition of GFP-tagged Sortilin (unknown origin) expressed in HEK293T cells after 42 hrs by FACS analysis | Homo sapiens | 1 | ALA4627347 | cell-based format | Scientific Literature | |
9. | ALA4630496 | A | Substrate activity at human SORT1 expressed in HEK293 cells assessed as compound uptake at 100 nM incubated for 1 hr by confocal microscopy | Homo sapiens | 2 | ALA4627413 | cell-based format | Scientific Literature | |
10. | ALA4630497 | A | Substrate activity at human SORT1 expressed in HEK293 cells assessed as compound uptake incubated for 2 hrs by flow cytometry | Homo sapiens | 2 | ALA4627413 | cell-based format | Scientific Literature |