# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA761500 | B | Inhibition of pancreatic cholesterol esterase using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substrates | Bos taurus | 4 | ALA1150502 | single protein format | Scientific Literature | |
2. | ALA1119694 | B | Inhibition of human LAL after 30 mins by fluorescence assay | Homo sapiens | 8 | ALA1155456 | single protein format | Scientific Literature | |
3. | ALA1119695 | B | Inhibition of human LAL at 10 uM after 30 mins by fluorescence assay | Homo sapiens | 20 | ALA1155456 | single protein format | Scientific Literature | |
4. | ALA1119696 | B | Competitive inhibition of human LAL preincubated for 30 mins by Lineweaver-Burke plot analysis | Homo sapiens | 1 | ALA1155456 | single protein format | Scientific Literature | |
5. | ALA1119697 | B | Inhibition of human LAL at 833 nM by fluorescence assay | Homo sapiens | 7 | ALA1155456 | single protein format | Scientific Literature | |
6. | ALA1119698 | B | Inhibition of human LAL assessed as enzyme decarbamoylation rate constant at 10 uM after 30 mins by fluorescence assay | Homo sapiens | 8 | ALA1155456 | single protein format | Scientific Literature | |
7. | ALA1119699 | B | Inhibition of LAL in human GM05659 cell lysate assessed as reduction in lysosomal storage organelle cholesterol level at 0.1 to 10 uM after 4 days by bicinchoninic acid assay | Homo sapiens | 8 | ALA1155456 | assay format | Scientific Literature | |
8. | ALA1119817 | B | Inhibition of LAL in human GM05659 cell lysate assessed as reduction in lysosomal storage organelle cholesterol level at 0.1 to 10 uM treated for 3 days measured after 1 day of compound withdrawal by bicinchoninic acid assay | Homo sapiens | 3 | ALA1155456 | assay format | Scientific Literature | |
9. | ALA1119818 | B | Inhibition of LAL in intact human GM03123 cells assessed as reduction in lysosomal storage organelle cholesterol level at 10 uM after 3 days by filipin LSO assay | Homo sapiens | 2 | ALA1155456 | cell-based format | Scientific Literature | |
10. | ALA1119819 | B | Inhibition of LAL in intact human GM05659 cells assessed as increase in neutral lipid accumulation in lysosomal storage organelle at 10 uM after 3 days by lipidTox green staining-based fluorescence microscopy | Homo sapiens | 2 | ALA1155456 | cell-based format | Scientific Literature |