| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3830811 | B | Inhibition of human 17-beta-HSD14 using estradiol as substrate after 15 mins by fluorimetric assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA3830812 | B | Binding affinity to human 17-beta-HSD14 assessed as change in melting temperature at 0.25 mM by thermal shift assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA3861912 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS at 1 uM using [3H]-E2 substrate and NAD+ incubated for 2 hrs using bacterial suspension by HPLC based radioactive displacement assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 4. | ALA3861916 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS at 100 uM uM using E2 substrate and NAD+ incubated for 2 hrs using purified enzyme by fluorimetric assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA3861917 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS at 2 uM using [3H]-E2 substrate and NAD+ incubated for 2 hrs using purified enzyme by fluorimetric assay | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 6. | ALA3861918 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 hrs using purified enzyme by fluorimetric assay | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 7. | ALA3861919 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 hrs in presence of 0.5% v/v Tween 20 using purified enzyme by fluorimetric assay | Homo sapiens | 31 | assay format | Scientific Literature | ||
| 8. | ALA3861920 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 hrs in absence of 0.5% v/v Tween 20 using purified enzyme by fluorimetric assay | Homo sapiens | 31 | assay format | Scientific Literature | ||
| 9. | ALA3861924 | B | Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS at 22.2 uM using E2 substrate and NAD+ incubated for 2 hrs using purified enzyme by fluorimetric assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4155465 | B | Binding affinity to recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain using E2 as substrate in presence of NAD measured continuously for 15 mins by fluorimetric method | Homo sapiens | 17 | assay format | Scientific Literature | ||
| 11. | ALA4155466 | B | Inhibition of recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain at 100 uM using E2 as substrate in presence of NAD measured continuously for 15 mins by fluorimetric method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4155467 | B | Inhibition of recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain at 2 uM using E2 as substrate in presence of NAD measured continuously for 15 mins by fluorimetric method | Homo sapiens | 1 | assay format | Scientific Literature |
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