# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5149477 | B | Agonist activity at human Nectin-4 expressed in Jurkat T cells co-expressing response element driven luciferase reporter gene assessed as luminescence measured after 6 hrs by HT1376/CD137 reporter co-culture assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA5149478 | B | Binding affinity to human Nectin-4 assessed as dissociation constant using 1:1 Nectin-4/CD137 by surface plasmon resonance analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA5217337 | B | Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibition constant measured at 5 to 10 mins interval for 60 mins by fluorescence polarization assay | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
4. | ALA5217342 | B | Binding affinity to C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as dissociation constant by SPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature |