| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA702028 | B | Compound was evaluated for ex vivo inhibition of Kynurenine 3-hydroxylase activity in Kidney from Gerbils after injecting perorally | Gerbillinae | 4 | tissue-based format | Scientific Literature | ||
| 2. | ALA702029 | B | Compound was evaluated for ex vivo inhibition of Kynurenine 3-hydroxylase activity in Liver from Gerbils after injecting perorally | Gerbillinae | 4 | tissue-based format | Scientific Literature | ||
| 3. | ALA702030 | B | Compound was evaluated for ex vivo inhibition of Kynurenine 3-hydroxylase activity in brain from Gerbils after injecting perorally | Gerbillinae | 4 | tissue-based format | Scientific Literature | ||
| 4. | ALA702031 | B | Percent inhibition of kynurenine 3-hydroxylase, when 30 umol/kg of compound was administered orally in gerbil kidney and liver | Gerbillinae | 1 | assay format | Scientific Literature | ||
| 5. | ALA702032 | B | Percent inhibition of kynurenine 3-hydroxylase, when 30 umol/kg of compound was administered orally in gerbils | Gerbillinae | 1 | single protein format | Scientific Literature | ||
| 6. | ALA881158 | B | Compound was evaluated for inhibition of human recombinant KYN 3-OHase | 2 | single protein format | Scientific Literature | |||
| 7. | ALA842820 | B | Compound was evaluated for inhibition of human recombinant KYN 3-OHase. | 1 | single protein format | Scientific Literature | |||
| 8. | ALA1219092 | B | Inhibition of kynurenine 3-monooxygenase in human prefrontal cortex homogenates at 100 uM | Homo sapiens | 1 | tissue-based format | Scientific Literature | ||
| 9. | ALA3413142 | B | Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis | Homo sapiens | 64 | single protein format | Scientific Literature | ||
| 10. | ALA3413143 | B | Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysis | Homo sapiens | 64 | cell-based format | Scientific Literature | ||
| 11. | ALA3413308 | B | Inhibition of KMO in human PBMC | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 12. | ALA3414283 | B | Inhibition of KMO (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA3536664 | A | Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 14. | ALA3536667 | A | Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis in presence of 3 mg/ml plasma protein | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3536674 | A | Inhibition of KMO (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3630810 | B | Inhibition of human KMO | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 17. | ALA3636891 | B | Inhibition of kynurenine monooxygenase (unknown origin) by MS rapidfire assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 18. | ALA3871819 | B | Inhibition of human KMO | Homo sapiens | 51 | single protein format | Scientific Literature | ||
| 19. | ALA4011242 | B | Inhibition of KMO (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4012392 | B | Inhibition of recombinant full-length human N-terminal GST tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using L-kynurenine as substrate measured after 2 hrs in presence of NADPH by RapidFire mass spectrometric method | Homo sapiens | 33 | assay format | Scientific Literature |
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