# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA768408 | B | The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1C (SH-PTP1) (human PTPases.) | 2 | single protein format | Scientific Literature | |||
2. | ALA801964 | B | First-order rate constant (K inact) for conversion of the ExI complex (SHP 1 protein -inhibitor complex) into the covalent adduct, EI was determined using PNP as substrate | 2 | single protein format | Scientific Literature | |||
3. | ALA801965 | B | Dissociation constant towards SHP 1 receptor-inhibitor complex was determined using PNP as substrate | 2 | single protein format | Scientific Literature | |||
4. | ALA801966 | B | Inhibitory activity against Protein tyrosine phosphatase SHP-1. | 5 | single protein format | Scientific Literature | |||
5. | ALA844570 | B | Ratio between dissociation constant and First-order rate constant (Ki / K inact) of SHP 1 was determined | 2 | single protein format | Scientific Literature | |||
6. | ALA827002 | B | Dissociation constant for the interaction with the GST-N-SH2 domain of SHP-1 | 14 | single protein format | Scientific Literature | |||
7. | ALA828855 | B | Dissociation constant for the interaction with the GST-N-SH2 domain of SHP-1; nb is no binding | 6 | single protein format | Scientific Literature | |||
8. | ALA828133 | B | Concentration required to stimulate SHP-1 enzymatic activity by 50% | 14 | single protein format | Scientific Literature | |||
9. | ALA829183 | B | Concentration required to stimulate SHP-1 enzymatic activity by 50%; not active | 6 | single protein format | Scientific Literature | |||
10. | ALA869488 | B | Inhibition of SHP1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA906836 | B | Inhibition of SHP-1 catalytic domain | 2 | single protein format | Scientific Literature | |||
12. | ALA1806342 | B | Inhibition of catalytic domain of SHP-1 expressed in Escherichia coli assessed as p-nitrophenol release from pNPP substrate preincubated for 10 mins | 1 | assay format | Scientific Literature | |||
13. | ALA1804487 | B | Inhibition of SHP1 | 3 | single protein format | Scientific Literature | |||
14. | ALA1798839 | B | Inhibition of SHP1 | 9 | single protein format | Scientific Literature | |||
15. | ALA1828248 | B | Inhibition of human recombinant SHP1 in Tris buffer at pH 8 using OMPF as substrate | Homo sapiens | 19 | single protein format | Scientific Literature | ||
16. | ALA1828249 | B | Inhibition of human recombinant SHP1 in Tris buffer of pH 8 at 20 ug/mL | Homo sapiens | 7 | single protein format | Scientific Literature | ||
17. | ALA1826223 | B | Inhibition of human SHP1 by high-throughput screening | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA2067115 | B | Induction of SHP1 activation in human PLC5 cells at 1 to 15 uM after 24 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA2067117 | B | Induction of SHP1 activation in IL-6-stimulated human PLC5 cells assessed as reduction of p-STAT3 at 10 uM after 24 hrs by ELISA | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
20. | ALA2067118 | B | Induction of SHP1 activation in human PLC5 cell lysate at 10 uM after 24 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature |