# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA682484 | B | Inhibition constant against Escherichia coli cyclopropane fatty acid synthase | Escherichia coli | 10 | single protein format | Scientific Literature | ||
2. | ALA873666 | B | Inhibition of fatty acid synthase at a concentration of 150 (uM) | 33 | single protein format | Scientific Literature | |||
3. | ALA828726 | B | Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cells | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
4. | ALA858886 | B | Inhibitory activity against human FAS1 at 100 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA863392 | B | Inhibitory activity against human FAS1 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
6. | ALA862461 | B | Inhibition of FAS | Homo sapiens | 14 | single protein format | Scientific Literature | ||
7. | ALA862462 | B | Inhibition of FAS at 100 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA869274 | B | Inhibition of human FAS | Homo sapiens | 25 | single protein format | Scientific Literature | ||
9. | ALA2114818 | F | PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay. (Class of assay: confirmatory) | Homo sapiens | 1,011 | assay format | PubChem BioAssays | ||
10. | ALA2114932 | F | PubChem BioAssay. Dose response confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay. (Class of assay: confirmatory) | Homo sapiens | 1,011 | assay format | PubChem BioAssays | ||
11. | ALA960231 | B | Inhibition of fatty acid synthase | 2 | single protein format | Scientific Literature | |||
12. | ALA985841 | B | Inhibition of FAS in human ZR-75-1 cells by spectrophotometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA1260142 | B | Inhibition of FAS | 13 | single protein format | Scientific Literature | |||
14. | ALA1260143 | B | Inhibition of FAS at 1000 uM | 1 | single protein format | Scientific Literature | |||
15. | ALA1839595 | B | Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
16. | ALA2090544 | B | Inhibition of FASN in human SK-BR-3 cells assessed as oxidation of NADPH at 21 uM after 24 hrs by Spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA2090545 | B | Inhibition of FASN in human SK-BR-3 cells assessed as oxidation of NADPH at 74 uM after 24 hrs by Spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA2090546 | B | Inhibition of FASN in human SK-BR-3 cells assessed as oxidation of NADPH at 41 uM after 24 hrs by Spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA2090548 | B | Inhibition of FASN in human SK-BR-3 cells assessed as oxidation of NADPH at 29 uM after 24 hrs by Spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA2090549 | B | Inhibition of FASN in human SK-BR-3 cells assessed as oxidation of NADPH at 28 uM after 24 hrs by Spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |