# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA670877 | F | Stimulating GH secretion in dogs after oral administration at dose of 1 mg/kg | Sus scrofa | 6 | organism-based format | Scientific Literature | ||
2. | ALA684262 | F | Compound was evaluated for GH release for effect on human GH secretagogue receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA677173 | B | Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor | Homo sapiens | 12 | single protein format | Scientific Literature | ||
4. | ALA685171 | B | Binding affinity towards human pituitary Growth hormone secretagogue receptor using [125I][Tyr4]-ghrelin as radioligand | 21 | single protein format | Scientific Literature | |||
5. | ALA685172 | B | Inhibition of ghrelin binding to Growth hormone secretagogue receptor expressed in BHK cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
6. | ALA685173 | B | Inhibitory concentration (biotinylated probe) is evaluated for [35S]- MK-0677 binding | 1 | single protein format | Scientific Literature | |||
7. | ALA685174 | B | Compound was evaluated for binding affinity using [35S]MK-0677 (800-1100 Ci/mmol), as radioligand having specific high activity | 1 | single protein format | Scientific Literature | |||
8. | ALA685177 | B | Binding Affinity against Growth hormone secretagogue receptor of swine using [35S]MK-0677 as radioligand | Sus scrofa | 4 | single protein format | Scientific Literature | ||
9. | ALA685178 | B | Binding affinity towards human Growth hormone secretagogue receptor type 1 using competitive binding assay with radiolabeled [35S]-MK-0677 expressed as IC50 | Homo sapiens | 10 | single protein format | Scientific Literature | ||
10. | ALA685179 | B | Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]MK-0677 as a radiolabeled ligand | 27 | single protein format | Scientific Literature | |||
11. | ALA685180 | B | Inhibition against human growth hormone secretagogue (GHS) receptor | 3 | single protein format | Scientific Literature | |||
12. | ALA685181 | B | Inhibition against human growth hormone secretagogue (GHS) receptor; No binding detected | 1 | single protein format | Scientific Literature | |||
13. | ALA685782 | B | Ability to displace [125I]ghrelin from cloned human Growth hormone secretagogue receptor type I (GSH1a) expressed in COS-7 cells | 2 | cell-based format | Scientific Literature | |||
14. | ALA685783 | B | Ability to displace [125I]ghrelin from cloned human Growth hormone secretagogue receptor type I (GSH1a) receptor expressed in COS-7 cells | 1 | cell-based format | Scientific Literature | |||
15. | ALA685784 | B | Binding affinity towards cloned human Growth hormone secretagogue receptor type I in LLC PK-1 cells using [125I][His9]-ghrelin as radioligand | 21 | cell-based format | Scientific Literature | |||
16. | ALA697754 | F | Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
17. | ALA696853 | B | In vitro binding affinity against human type 1a growth hormone secretagogue receptor (hGHS-R1a), using [125I]ghrelin as radioligand. | 5 | single protein format | Scientific Literature | |||
18. | ALA810796 | F | Tested for in vivo activity against GH release after iv administration in swine | Sus scrofa | 12 | organism-based format | Scientific Literature | ||
19. | ALA839691 | B | Binding affinity for human growth hormone secretagogue receptor was determined using [125I]ghrelin | Homo sapiens | 13 | single protein format | Scientific Literature | ||
20. | ALA828977 | B | Binding affinity for human growth hormone secretagogue receptor using [125I]ghrelin; NA means not active | Homo sapiens | 3 | single protein format | Scientific Literature |