| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA680700 | B | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | 5 | cell-based format | Scientific Literature | |||
| 2. | ALA680701 | B | Binding affinity for Excitatory amino acid transporter 3 (EAAT-3) in Glu uptake system | 11 | single protein format | Scientific Literature | |||
| 3. | ALA680706 | F | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 3 (EAAT3) | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA680707 | F | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 3 (EAAT3) | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA881964 | B | Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 3 | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 6. | ALA859749 | F | Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 7. | ALA870602 | B | Activity against human EAAT3 transfected in HEK293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA907704 | F | Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA907707 | F | Substrate activity at human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA907710 | F | Substrate activity at human EAAT3 expressed in HEK293 cells at 1000 uM relative to glutamate by FLIPR membrane potential assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA1016589 | B | Inhibition of glutamate-induced depolarization in human EAAT3 expressed in HEK293 cells by FMP assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 12. | ALA1013069 | B | Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 13. | ALA998474 | B | Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cells | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 14. | ALA998477 | B | Activity of human EAAT3 expressed in HEK293 cells up to 100 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA998480 | B | Activity at human EAAT3 expressed in HEK293 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA974563 | B | Inhibition of [3H]D-aspartate uptake at human EAAT3 expressed in mouse C17.2 cells at 100 uM relative to control | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 17. | ALA974566 | B | Inhibition of [14C]glutamate uptake at human EAAT3 expressed in african green monkey COS1 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA974567 | B | Displacement of [3H]D-aspartate from human EAAT3 expressed in mouse C17.2 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA1259929 | B | Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 20. | ALA1261603 | B | Inhibition of human EAAT3 expressed in HEK293 cells at 75 uM by [3H]D-Asp uptake assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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