# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA661349 | F | Percent activation of wild type CFTR dependent efflux was determined by measuring the rate of iodide [125I]- efflux from transfected CHO cells | 26 | ALA1148470 | cell-based format | Scientific Literature | ||
2. | ALA661350 | F | Percent activation of wild type CFTR dependent efflux was determined by measuring the rate of iodide [125I]- efflux from transfected CHO cells; ND = not determined | 2 | ALA1148470 | cell-based format | Scientific Literature | ||
3. | ALA665292 | F | Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 uM Fsk | 8 | ALA1148470 | assay format | Scientific Literature | ||
4. | ALA665293 | F | Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 uM Fsk | 8 | ALA1148470 | assay format | Scientific Literature | ||
5. | ALA833631 | F | Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR | Homo sapiens | 43 | ALA1143534 | cell-based format | Scientific Literature | |
6. | ALA853576 | F | Potentiation of deltaF508 mutated CFTR dependent iodide influx at 0.1 uM | 1 | ALA1149376 | assay format | Scientific Literature | ||
7. | ALA902267 | B | Inhibition of CFRT-mediated chloride transport in human bronchial epithelial cells by voltage clamp method | Homo sapiens | 1 | ALA1138384 | cell-based format | Scientific Literature | |
8. | ALA944926 | B | Binding affinity to GST tagged human CFTR PDZ2 domain | Homo sapiens | 5 | ALA1141464 | single protein format | Scientific Literature | |
9. | ALA944928 | B | Binding affinity to GST tagged human CFTR PDZ2 domain upto 300 uM | Homo sapiens | 1 | ALA1141464 | single protein format | Scientific Literature | |
10. | ALA936826 | B | Activity at human wild type CFTR expressed in CHO cells assessed as forskolin stimulated iodide flux | Homo sapiens | 1 | ALA1145498 | cell-based format | Scientific Literature | |
11. | ALA939224 | B | Activity at human wild type CFTR expressed in Calu3 cells assessed as forskolin stimulated iodide flux | Homo sapiens | 1 | ALA1145498 | cell-based format | Scientific Literature | |
12. | ALA939223 | B | Activity at human wild type CFTR expressed in F508del-CF1 cells assessed as forskolin stimulated iodide flux | Homo sapiens | 1 | ALA1145498 | cell-based format | Scientific Literature | |
13. | ALA928174 | B | Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx at 10 uM | Homo sapiens | 3 | ALA1144813 | cell-based format | Scientific Literature | |
14. | ALA928175 | B | Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx at 25 uM | Homo sapiens | 3 | ALA1144813 | cell-based format | Scientific Literature | |
15. | ALA928176 | B | Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx | Homo sapiens | 9 | ALA1144813 | cell-based format | Scientific Literature | |
16. | ALA982872 | F | Agonist activity at CFTR-deltaF508 mutant expressed in NIH3T3 cells assessed as increase in forskolin-stimulated current | 2 | ALA1155125 | cell-based format | Scientific Literature | ||
17. | ALA982873 | F | Agonist activity at CFTR-deltaF508 mutant expressed in NIH3T3 cells assessed as increase in forskolin-stimulated current at 30 uM by whole cell assay relative to control | 1 | ALA1155125 | cell-based format | Scientific Literature | ||
18. | ALA982874 | F | Agonist activity at CFTR-deltaF508 mutant expressed in NIH3T3 cells assessed as increase in forskolin-stimulated current at 30 uM by whole cell assay relative to genistein | 1 | ALA1155125 | cell-based format | Scientific Literature | ||
19. | ALA982876 | F | Agonist activity at CFTR-K1250A mutant assessed as increase in forskolin-stimulated current at 5 uM | Homo sapiens | 1 | ALA1155125 | assay format | Scientific Literature | |
20. | ALA985680 | F | Agonist activity at CFTR-deltaF508 mutant expressed in NIH3T3 cells assessed as increase in forskolin-stimulated current at 20 uM by whole cell assay relative to control | 2 | ALA1155125 | cell-based format | Scientific Literature |