# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA856950 | B | Binding affinity of compound (10 uM) towards D284A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 5 | cell-based format | Scientific Literature | |||
2. | ALA651921 | B | Binding affinity of compound (10 uM) towards E291Q receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 2 | cell-based format | Scientific Literature | |||
3. | ALA651922 | B | Binding affinity of compound (10 uM) towards E291Q receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells: Inactive | 1 | cell-based format | Scientific Literature | |||
4. | ALA651923 | B | Binding affinity of compound (10 uM) towards E291Q receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells; Inactive | 2 | cell-based format | Scientific Literature | |||
5. | ALA651924 | B | Binding affinity of compound (10 uM) towards H121A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 5 | cell-based format | Scientific Literature | |||
6. | ALA651925 | B | Binding affinity of compound (10 uM) towards H121A/T292A receptor variant (double mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 3 | cell-based format | Scientific Literature | |||
7. | ALA651926 | B | Binding affinity of compound (10 uM) towards H121F receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 5 | cell-based format | Scientific Literature | |||
8. | ALA651927 | B | Binding affinity of compound (10 uM) towards Q288A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 5 | cell-based format | Scientific Literature | |||
9. | ALA651928 | B | Binding affinity of compound (10 uM) towards T290A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 4 | cell-based format | Scientific Literature | |||
10. | ALA651929 | B | Binding affinity of compound (10 uM) towards T290A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells; Not tested | 1 | cell-based format | Scientific Literature | |||
11. | ALA651930 | B | Binding affinity of compound (10 uM) towards T292A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 5 | cell-based format | Scientific Literature | |||
12. | ALA651931 | B | Binding affinity of compound (10 uM) towards Y1210A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 4 | cell-based format | Scientific Literature | |||
13. | ALA651932 | B | Binding affinity of compound (10 uM) towards Y1210A receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells; Inactive | 1 | cell-based format | Scientific Literature | |||
14. | ALA651933 | B | Binding affinity of compound (10 uM) towards Y210A-292A receptor variant (double mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 2 | cell-based format | Scientific Literature | |||
15. | ALA650748 | B | Binding affinity of compound (10 uM) towards Y210A-292A receptor variant (double mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells: Inactive | 1 | cell-based format | Scientific Literature | |||
16. | ALA650749 | B | Binding affinity of compound (10 uM) towards Y210A-292A receptor variant (double mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells; Inactive | 2 | cell-based format | Scientific Literature | |||
17. | ALA875065 | B | Binding affinity of compound (10 uM) towards Y49F receptor variant (mutant CCR2 receptor) using radioligand [125I]MCP-1 in HEK 293 cells | 5 | cell-based format | Scientific Literature | |||
18. | ALA650750 | B | Binding affinity relative to indolopiperidine (compound 1) for C-C chemokine receptor type 2B was determined | 1 | single protein format | Scientific Literature | |||
19. | ALA650751 | F | Inhibition of chemotactic protein to CCR2b | 1 | assay format | Scientific Literature | |||
20. | ALA655683 | F | Compound was evaluated for the antagonist activity against C-C chemokine receptor type 2 | 2 | assay format | Scientific Literature |