| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA662980 | B | Ex vivo inhibitory activity against human choline kinase was determined | 5 | single protein format | Scientific Literature | |||
| 2. | ALA662981 | B | Compound was tested ex vivo for inhibition against purified choline kinase obtained from yeast | Saccharomyces cerevisiae | 10 | single protein format | Scientific Literature | ||
| 3. | ALA828518 | B | Inhibitory activity against human choline kinase enzyme | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 4. | ALA832433 | B | Ex vivo inhibitory concentration against human choline kinase | Homo sapiens | 41 | single protein format | Scientific Literature | ||
| 5. | ALA1912789 | B | Inhibition of recombinant human Choline kinase alpha using [methyl-14C]choline chloride as substrate after 30 mins by autoradiography | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 6. | ALA1772322 | B | Inhibition of ChoK in HT29 cells using [methyl-14C]choline chloride as substrate after 14 hrs by radiography | 2 | cell-based format | Scientific Literature | |||
| 7. | ALA3117184 | B | Binding affinity to human CK-alpha1 by tryptophan fluorescence spectroscopic analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA3227786 | B | Inhibition of CHKA in human HCT116 cells assessed as [3H]phosphocholine formation using [3H]choline chloride as substrate at 2.4 +/-1 uM incubated for 1 hr prior to substrate addition measured after 1 hr by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3227787 | B | Inhibition of CHKA in human HCT116 cells assessed as [3H]phosphocholine formation using [3H]choline chloride as substrate at 6.5 +/-4 uM incubated for 1 hr prior to substrate addition measured after 1 hr by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3227789 | B | Inhibition of CHKA in human HCT116 cells assessed as [3H]phosphocholine formation using [3H]choline chloride as substrate incubated for 1 hr prior to substrate addition measured after 1 hr by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3734544 | B | Inhibition of recombinant CK-alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 5 | cell-based format | Patent Bioactivity Data | ||
| 12. | ALA3769127 | B | Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 13. | ALA3769131 | B | Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) assessed as ligand residence time by surface plasmon resonance assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 14. | ALA3769132 | B | Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) assessed as association rate constant by surface plasmon resonance assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 15. | ALA3769133 | B | Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled ATP regeneration assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 16. | ALA3766469 | B | Inhibition of ChoKalpha in human MDA-MB-468 cells assessed as reduction in phosphocholine level after 24 hrs by NMR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3766470 | B | Inhibition of ChoKalpha in human MDA-MB-415 cells assessed as reduction in phosphocholine level after 24 hrs by NMR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3766475 | B | Inhibition of recombinant human ChoKalpha using choline as substrate by ultraviolet spectroscopic assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3766476 | B | Reversible binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) ChoKalpha1 by STD NMR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4015086 | B | Inhibition of human CHKalpha (1 to 457 residues) by ADP Glo HTS assay | Homo sapiens | 1 | single protein format | Scientific Literature |
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