# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA677463 | B | In vitro binding affinity towards Endothelial differentiation G-protein coupled receptor 1 in CHO cells using [3H]S1P as radioligand relative to SIP | 4 | cell-based format | Scientific Literature | |||
2. | ALA677464 | B | In vitro binding affinity towards Endothelial differentiation G-protein coupled receptor 1 in CHO cells using [3H]S1P as radioligand relative to SIP; Not active | 2 | cell-based format | Scientific Literature | |||
3. | ALA805799 | B | In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells using [gamma-35S]-GTP as radioligand | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
4. | ALA800919 | B | In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells using [gamma-35S]-GTP as radioligand (Experiment 1) | 1 | cell-based format | Scientific Literature | |||
5. | ALA800920 | B | In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells using [gamma-35S]-GTP as radioligand. (Experiment 2) | 1 | cell-based format | Scientific Literature | |||
6. | ALA800921 | B | Binding affinity to human Sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligand | 26 | cell-based format | Scientific Literature | |||
7. | ALA800922 | B | Binding affinity to human sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligand | 27 | cell-based format | Scientific Literature | |||
8. | ALA806166 | B | Binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligand | 1 | cell-based format | Scientific Literature | |||
9. | ALA806167 | B | Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
10. | ALA807603 | B | Percent binding affinity to displace radioligand [3H]SIP from Sphingosine 1-phosphate receptor Edg-1 expressed in CHO cells | 4 | cell-based format | Scientific Literature | |||
11. | ALA830091 | B | Effective concentration against sphingosine-1-phosphate receptor 1 determined by a [c-35S]-GTP binding assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
12. | ALA839767 | F | Agonism of human S1P-1 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]GTP-gamma-S as radioligand | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA829014 | B | Effective concentration against sphingosine-1-phosphate receptor 1 determined by a [c-35S]-GTP binding assay; no agonist activity | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA830044 | B | In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioligand | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA832506 | B | In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioligand; partial agonist | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
16. | ALA830223 | B | Maximal efficacy against sphingosine-1-phosphate receptor 1 determined by a [c-35S]-GTP binding assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
17. | ALA833009 | B | Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranes | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
18. | ALA880429 | B | Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 1 expressed in CHO cells | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
19. | ALA864561 | F | Binding potency at human S1P1 receptor by [35S]GTP-gamma-S binding assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
20. | ALA864564 | F | Efficacy at human S1P1 receptor by [35S]GTP-gamma-S binding assay | Homo sapiens | 5 | assay format | Scientific Literature |