| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4392899 | B | Induction of human TLR1 homodimerization expressed in insect Hi5 cells by size exclusion chromatography | Homo sapiens | 2 | ALA4392821 | cell-based format | Scientific Literature | |
| 2. | ALA4429216 | B | Agonist activity at wild-type human TLR1 expressed in HEK293 cells up to 25 uM measured after 6 hrs by NF-kappaB luciferase reporter gene assay | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 3. | ALA4622262 | B | Antagonist activity at TLR1 in human PBMC assessed as inhibition of Pam3CSK4-induced TNFalpha production preincubated for 30 mins followed by Pam3CSK4 addition and measured after 20 hrs by HTRF assay | Homo sapiens | 1 | ALA4619804 | cell-based format | Scientific Literature | |
| 4. | ALA5039719 | B | Agonist activity at TLR1 in HEK-Blue hTLR2 cells at 0.2 uM incubated for 24 hrs in presence of anti-hTLR1-IgG antibodies measured by Quanti-Blue based SEAP assay | Homo sapiens | 1 | ALA5038589 | cell-based format | Scientific Literature |
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