# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3819944 | B | Activation of TRAAK (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA3819958 | B | Inhibition of of human TRAAK expressed in HEK293 cells assessed as reduction in channel currents at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA3993346 | B | Agonist activity at TRAAK (unknown origin) expressed in HEK293 cells assessed as increase in K+ current at 20 uM measured at +60 mV by whole-cell patch clamp method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA3993347 | B | Agonist activity at TRAAK (unknown origin) expressed in HEK293 cells assessed as increase in K+ current at 10 uM measured at +60 mV by whole-cell patch clamp method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3993348 | B | Agonist activity at TRAAK (unknown origin) expressed in HEK293 cells assessed as increase in K+ current at 100 uM measured at +60 mV by whole-cell patch clamp method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4359048 | B | Activation of recombinant human TRAAK expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clamp electrophysiological analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4359050 | B | Activation of recombinant human TRAAK expressed in HEK293T cells assessed as increase in K+ current amplitude at 10 uM by whole cell voltage clamp electrophysiological analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4359068 | B | Activation of recombinant human TRAAK D227Y mutant expressed in HEK293T cells assessed as increase in K+ current amplitude at 10 uM by whole cell voltage clamp electrophysiological analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4419085 | B | Activation of K2P4.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4419088 | B | Activation of K2P4.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at 100 uM at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4419096 | B | Binding affinity to K2P4.1 (unknown origin) assessed as induction of protein cross linking and labelling at 1 to 200 uM following 254 nm UV light irradiation for 30 secs by SDS-PAGE analysis | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
12. | ALA4421813 | B | Activation of K2P4.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4421815 | B | Activation of K2P4.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential at 100 uM by two-electrode voltage clamp assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4421825 | B | Binding affinity to purified TRAAK (unknown origin) at 1 to 200 uM following exposure to 254 nm UV light for 30 secs by SDS-PAGE and streptavidin-HRP detection based assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
15. | ALA4421854 | B | Activation of K2P4.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA4667313 | B | Activation of K2P4.1 (unknown origin) at 30 uM by manual patch clamp method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
17. | ALA4670290 | B | Inhibition of human TRAAK at intermediate transition state expressed in CHO cells by whole-cell patch-clamp electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA5100507 | B | Inhibition of human TRAAK expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature |