# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3424649 | Binding | Inhibition of PARP1 (unknown origin) | Homo sapiens | 6 | ALA3421544 | single protein format | Scientific Literature | |
2. | ALA3424650 | Binding | Inhibition of PARP1 (unknown origin) at 1 uM | Homo sapiens | 15 | ALA3421544 | single protein format | Scientific Literature | |
3. | ALA3424684 | Binding | Inhibition of PARP1 (unknown origin) at 2.8 uM | Homo sapiens | 1 | ALA3421544 | single protein format | Scientific Literature | |
4. | ALA3428885 | Binding | Inhibition of PARP1 (unknown origin) | Homo sapiens | 17 | ALA3425485 | single protein format | Scientific Literature | |
5. | ALA3579452 | Binding | Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity using NAD+ by chemiluminescence detection based assay | Homo sapiens | 8 | ALA3576815 | assay format | Scientific Literature | |
6. | ALA3591900 | Binding | Inhibition of human PARP1 | Homo sapiens | 6 | ALA3588759 | single protein format | Scientific Literature | |
7. | ALA3595281 | Binding | Inhibition of full-length human ARTD1 using 500 nM NAD substrate after 1 hr incubation | Homo sapiens | 4 | ALA3593161 | single protein format | Scientific Literature | |
8. | ALA3594610 | Binding | Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein at 10 uM after 60 mins by TACS-Sapphire substarte-based colorimetric analysis relative to control | Homo sapiens | 13 | ALA3593177 | single protein format | Scientific Literature | |
9. | ALA3594611 | Binding | Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein after 60 mins by TACS-Sapphire substarte-based colorimetric analysis | Homo sapiens | 23 | ALA3593177 | single protein format | Scientific Literature | |
10. | ALA3607346 | Binding | Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assay | Homo sapiens | 59 | ALA3603755 | single protein format | Scientific Literature | |
11. | ALA3607349 | Binding | Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measured after 15 mins by immunocytochemical analysis | Homo sapiens | 26 | ALA3603755 | cell-based format | Scientific Literature | |
12. | ALA3607369 | Binding | Binding affinity to recombinant human HisGST-tagged PARP-1 catalytic domain by surface plasmon resonance analysis | Homo sapiens | 5 | ALA3603755 | single protein format | Scientific Literature | |
13. | ALA3607370 | Binding | Binding affinity to recombinant human HisGST-tagged PARP-1 catalytic domain assessed as dissociation half life by surface plasmon resonance analysis | Homo sapiens | 5 | ALA3603755 | single protein format | Scientific Literature | |
14. | ALA3619957 | Binding | Inhibition of PARP1 (unknown origin) | Homo sapiens | 14 | ALA3616447 | single protein format | Scientific Literature | |
15. | ALA3619268 | Binding | Inhibition of PARP1 (unknown origin) | Homo sapiens | 1 | ALA3616428 | single protein format | Scientific Literature | |
16. | ALA3631406 | Binding | Inhibition of PARP1 (unknown origin) by fluorescence analysis | Homo sapiens | 8 | ALA3627698 | single protein format | Scientific Literature | |
17. | ALA3738635 | Binding | Inhibition of PARP1 (unknown origin) incubated for 10 mins using biotinylated NAD+ and activated DNA by colorimetric assay | Homo sapiens | 8 | ALA3734737 | single protein format | Scientific Literature | |
18. | ALA3738636 | Binding | Inhibition of PARP1 in human G7 cells incubated for 60 mins by immunofluorescence assay | Homo sapiens | 2 | ALA3734737 | cell-based format | Scientific Literature | |
19. | ALA3738637 | Binding | Inhibition of PARP1 in human T98G cells incubated for 60 mins by immunofluorescence assay | Homo sapiens | 2 | ALA3734737 | cell-based format | Scientific Literature | |
20. | ALA3743825 | Binding | Inhibition of full length human PARP1 expressed in Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidin-horseradish peroxidase-based luminescence assay | Homo sapiens | 3 | ALA3739394 | cell-based format | Scientific Literature |