# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734223 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as increase in insulin release at 5 uM incubated for 2 hrs by ELISA | Mus musculus | 7 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
2. | ALA3734224 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as increase in insulin release at 2 to 10 uM incubated for 2 hrs in presence of high glucose media by ELISA | Mus musculus | 4 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
3. | ALA3734225 | B | Inhibition of GRK5 in mouse C2C12 cells assessed as increase of 2-NBDG uptake at 5 uM after 1 hr | Mus musculus | 3 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
4. | ALA3734255 | B | Inhibition of GRK5 in mouse C2C12 cells assessed as reduction in insulin secretion incubated for 2 hrs in presence of low glucose media by ELISA | Mus musculus | 4 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
5. | ALA3734257 | B | Inhibition of GRK5 in mouse C2C12 cells assessed as insulin-dependent increase of 2-NBDG uptake (Rvb = 11.78 +/- 1.22%) | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
6. | ALA3734269 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as ratio of insulin release at 2 uM incubated for 2 hrs by ELISA relative to DMSO (Rvb = 1 No_unit) | Mus musculus | 4 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
7. | ALA3734270 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as ratio of insulin release at 5 uM incubated for 2 hrs by ELISA relative to DMSO (Rvb = 1 No_unit) | Mus musculus | 4 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
8. | ALA3734271 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as ratio of insulin release at 10 uM incubated for 2 hrs by ELISA relative to DMSO (Rvb = 1 No_unit) | Mus musculus | 4 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
9. | ALA3734272 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as inhibition of insulin release at 5 uM incubated for 2 hrs by ELISA | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
10. | ALA3734273 | B | Inhibition of GRK5 in mouse BetaTC6 cells assessed as inhibition of insulin release incubated for 2 hrs by ELISA | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
11. | ALA3734276 | B | Inhibition of GRK5 in mouse C2C12 cells assessed as reduction in insulin secretion ratio incubated for 2 hrs in presence of low glucose media by ELISA relative to DMSO | Mus musculus | 2 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
12. | ALA3734278 | B | Inhibition of GRK5 in mouse C2C12 cells assessed as insulin release by ELISA | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data |