| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3779396 | B | Inhibition of human MOZ using histone H3 substrate at 10 uM incubated for 2 to 4 mins by SDS-PAGE based autoradiography in presence of [14C]acetyl-CoA relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4346058 | B | Inhibition of recombinant human GST-tagged Myst3 expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and [3H]acetyl-CoA as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 30 mins by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4374936 | B | Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl coenzyme A and N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin) as substrate incubated for 60 mins by Alpha screen technology | Homo sapiens | 72 | cell-based format | Scientific Literature | ||
| 4. | ALA4374938 | B | Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 15 uM acetyl coenzyme A and N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin) as substrate incubated for 60 mins by Alpha screen technology | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 5. | ALA4377336 | B | Inhibition of human MYST3 (unknown origin) up to 50 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4378996 | B | Inhibition of human MOZ at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4404752 | B | Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl coenzyme A and N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin) as substrate incubated for 60 mins by Alpha screen technology | Homo sapiens | 177 | cell-based format | Scientific Literature | ||
| 8. | ALA4404753 | B | Inhibition of recombinant KAT6A (unknown origin) expressed in C57BL/6 mouse embryonic fibroblasts assessed as reduction in cell proliferation supplemented with fresh medium containing compounds every 48 hrs after for 168 hrs under low oxygen condition | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 9. | ALA4404789 | B | Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 15 uM acetyl coenzyme A and N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin) as substrate incubated for 60 mins by Alpha screen technology | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 10. | ALA4407059 | B | Inhibition of KAT6A (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4619279 | B | Inhibition of MYST3 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4886588 | B | MYST3 (HAT) CEREP ligand profiling | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | |||
| 13. | ALA5123701 | B | Inhibition of human Myst3 using histone H3 peptide and acetyl-coA as substrates preincubated for 10 mins followed by substrate addition and measured after 30 mins by beckman scintillation counting analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5210050 | F | Affinity Phenotypic Cellular interaction (Growth inhibition assays in EMRK1184 lymphoma cells) EUB0000329a MYST3 | Homo sapiens | 1 | cell-based format | Literature data from EUbOPEN Chemogenomic Library | ||
| 15. | ALA5210510 | B | Affinity Biochemical interaction (AlphaScreen (HAT activity assay)) EUB0000327a MYST3 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
| 16. | ALA5210513 | B | Affinity Biochemical interaction (Surface plasmon resonance (SPR)) EUB0000329a MYST3 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
| 17. | ALA5214074 | B | Selectivity interaction (HAT panel) EUB0000329a MYST3 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
| 18. | ALA5214075 | B | Selectivity interaction (AlphaScreen) EUB0000329a MYST3 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library |
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